Gene: DDIAS
Official Full Name: DNA damage induced apoptosis suppressorprovided by HGNC
Gene Summary: Involved in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage and regulation of DNA stability. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28120 | DDIAS Knockout cell line (HeLa) | Human | DDIAS | 1:3~1:6 | Negative | Online Inquiry |
KO28121 | DDIAS Knockout cell line (HCT 116) | Human | DDIAS | 1:2~1:4 | Negative | Online Inquiry |
KO28122 | DDIAS Knockout cell line (HEK293) | Human | DDIAS | 1:3~1:6 | Negative | Online Inquiry |
KO28123 | DDIAS Knockout cell line (A549) | Human | DDIAS | 1:3~1:4 | Negative | Online Inquiry |
DDIAS Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study of gene function by providing researchers with precise deletions of specific genes. These knockout cell lines are generated through advanced genome editing techniques, such as CRISPR-Cas9, ensuring the complete removal of target gene sequences. By eliminating these genes, DDIAS Gene Knockout Cell Lines enable the examination of phenotypic consequences and the exploration of cellular pathways involved in various biological processes.
The key mechanism underlying the functionality of these cell lines involves targeted gene disruption, allowing researchers to observe how gene loss affects cellular behavior, signaling pathways, and overall physiological responses. This is crucial for elucidating gene roles in disease contexts, such as cancer, metabolic disorders, or regenerative medicine.
Scientifically, DDIAS Gene Knockout Cell Lines hold significant importance in both research and clinical applications. They serve as invaluable tools for drug discovery and development, providing insights into potential therapeutic targets and mechanisms of drug action. In academic settings, these cell lines support extensive studies in genetics, molecular biology, and biochemistry, paving the way for novel hypotheses and advanced scientific inquiry.
Compared to alternative models, such as transient knockdown systems or whole-organism approaches, DDIAS Gene Knockout Cell Lines offer unmatched precision and reproducibility. Researchers benefit from the stability of these cell lines, which allow for longitudinal studies and the ability to generate a vast array of subclones tailored to specific experimental needs.
The value of DDIAS Gene Knockout Cell Lines cannot be overstated; they empower researchers and clinicians to discover and validate the roles of genes in health and disease, ultimately accelerating the pace of scientific discovery and therapeutic innovation. Our company, with its expertise in advanced cellular technologies and commitment to quality, proudly offers these high-caliber gene knockout models, equipping you with the tools necessary to advance your research and clinical goals.
Please note that all services are for research use only. Not intended for any clinical use.
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