Gene: DCP2
Official Full Name: decapping mRNA 2provided by HGNC
Gene Summary: The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18371 | DCP2 Knockout cell line (HeLa) | Human | DCP2 | 1:3~1:6 | Negative | Online Inquiry |
KO18372 | DCP2 Knockout cell line (HCT 116) | Human | DCP2 | 1:2~1:4 | Negative | Online Inquiry |
KO18373 | DCP2 Knockout cell line (HEK293) | Human | DCP2 | 1:3~1:6 | Negative | Online Inquiry |
KO18374 | DCP2 Knockout cell line (A549) | Human | DCP2 | 1:3~1:4 | Negative | Online Inquiry |
DCP2 Gene Knockout Cell Lines are specialized cell line models engineered to specifically disrupt the expression of the DCP2 gene, a critical component involved in mRNA decapping and degradation. By utilizing CRISPR/Cas9 gene editing technology, these cell lines facilitate the precise knockout of DCP2, providing researchers with a powerful tool to study the gene's biological functions and its role in mRNA turnover.
The key mechanism of DCP2 involves its involvement in the decapping of mRNA molecules, which is vital for the regulation of gene expression. By creating cell lines that lack DCP2, researchers can elucidate the cellular consequences of diminished mRNA decapping, including impacts on gene regulation, RNA stability, and downstream signaling pathways. Such knockouts can further aid in understanding the broader implications of mRNA metabolism in various physiological and pathological contexts, including cancer and neurological disorders.
The scientific significance of DCP2 Gene Knockout Cell Lines lies in their potential applications in research settings, where they can serve as models for elucidating the role of mRNA decay in gene regulation and disease mechanisms. In clinical research, they may also inform the development of novel therapeutic strategies that target mRNA processing pathways.
One of the unique selling points of our DCP2 Gene Knockout Cell Lines is their high specificity and efficiency of gene disruption, combined with the reliable reproducibility of experimental results. Unlike traditional knockdown methods, which may yield transient effects, our knockout lines provide a stable and consistent platform for long-term studies. This stability is crucial for those seeking to understand the long-term implications of gene knockout on cellular behavior.
Researchers and clinicians seeking innovative and effective approaches to gene function studies will find DCP2 Gene Knockout Cell Lines valuable due to their robustness and relevance in gene regulation research. By employing these specialized cell lines, users can gain deeper insights into mRNA dynamics and their influences on cellular physiology.
Our company emphasizes expertise in developing cutting-edge biological tools tailored for the research community, ensuring that our products meet the highest scientific standards. With our commitment to quality and innovation, we are positioned as a leader in providing advanced models for genetic research, empowering scientists to explore the complexities of gene function with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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