Gene: DCP1B
Official Full Name: decapping mRNA 1Bprovided by HGNC
Gene Summary: This gene encodes a member of a family of proteins that function in removing the 5' cap from mRNAs, which is a step in regulated mRNA decay. This protein localizes to cytoplasmic foci which are the site of mRNA breakdown and turnover. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00970 | DCP1B Knockout cell line (Huh-7) | Human | DCP1B | 1:2~1:3 | Negative | Online Inquiry |
KO21444 | DCP1B Knockout cell line (HeLa) | Human | DCP1B | 1:3~1:6 | Negative | Online Inquiry |
KO21445 | DCP1B Knockout cell line (HCT 116) | Human | DCP1B | 1:2~1:4 | Negative | Online Inquiry |
KO21446 | DCP1B Knockout cell line (HEK293) | Human | DCP1B | 1:3~1:6 | Negative | Online Inquiry |
KO21447 | DCP1B Knockout cell line (A549) | Human | DCP1B | 1:3~1:4 | Negative | Online Inquiry |
DCP1B Gene Knockout Cell Lines are specialized cellular models designed to study the function of the DCP1B gene, which plays a crucial role in mRNA decapping, a vital process for gene expression regulation. These cell lines are engineered through precise genome editing techniques such as CRISPR-Cas9, resulting in the knockout of the DCP1B gene. This alteration enables researchers to meticulously examine the downstream effects of DCP1B deficiency, providing insights into mRNA stability, decay pathways, and their implications in various biological contexts.
The primary mechanism of action involves the disruption of the DCP1B-mediated mRNA decapping pathway, leading to an accumulation of capped mRNAs and the potential dysregulation of cellular homeostasis. By utilizing DCP1B Gene Knockout Cell Lines, researchers can investigate the gene's role in mRNA metabolism and its impact on protein synthesis and cellular signaling, thus drawing connections to disorders associated with dysfunctional mRNA management, including various types of cancer and neurodegenerative diseases.
From a scientific standpoint, these knockout cell lines are invaluable tools in both research and clinical applications. They serve as platforms for testing potential therapeutic targets and understanding molecular pathways, enabling the identification of novel biomarkers. The unique advantage of using DCP1B knockout models lies in their specificity—researchers can differentiate the effects of DCP1B loss from other mRNA regulatory pathways, which is often a challenge with non-specific inhibitors or overexpression systems.
For researchers, clinicians, and biotech professionals, the DCP1B Gene Knockout Cell Lines represent an essential resource for advancing our understanding of mRNA dynamics and their broader implications in health and disease. By providing rigorous and versatile models for experimentation, this product enhances the ability to develop targeted interventions that can lead to improved patient outcomes.
At our company, we pride ourselves on our expertise in genetic engineering and cell line development, delivering innovative biological products that support groundbreaking research and therapeutic advancements. Our commitment to quality and precision ensures that each DCP1B Gene Knockout Cell Line contributes to the rich landscape of molecular biology research.
Please note that all services are for research use only. Not intended for any clinical use.
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