Gene: DCAF4
Official Full Name: DDB1 and CUL4 associated factor 4provided by HGNC
Gene Summary: This gene encodes a WD repeat-containing protein that interacts with the Cul4-Ddb1 E3 ligase macromolecular complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28349 | DCAF4 Knockout cell line (HeLa) | Human | DCAF4 | 1:3~1:6 | Negative | Online Inquiry |
KO28350 | DCAF4 Knockout cell line (HCT 116) | Human | DCAF4 | 1:2~1:4 | Negative | Online Inquiry |
KO28351 | DCAF4 Knockout cell line (HEK293) | Human | DCAF4 | 1:3~1:6 | Negative | Online Inquiry |
KO28352 | DCAF4 Knockout cell line (A549) | Human | DCAF4 | 1:3~1:4 | Negative | Online Inquiry |
DCAF4 Gene Knockout Cell Lines are genetically engineered cellular models designed to study the functional implications of DCAF4, a gene implicated in various biological pathways, including cell cycle regulation and response to DNA damage. This advanced biological product employs the CRISPR-Cas9 technology for precise gene editing, resulting in the complete knockout of DCAF4 in selected cell lines. The resulting cell lines serve as essential tools for elucidating the role of DCAF4 in cellular processes and its connections to diseases such as cancer.
The key function of DCAF4 knockout cell lines lies in their ability to provide insights into the gene’s contribution to cellular mechanisms. Without DCAF4, researchers can investigate the compensatory pathways that may impact cell viability, proliferation, and survival under various stress conditions. This enables the assessment of potential therapeutic targets and the development of new strategies for treating diseases where DCAF4 plays a role.
In scientific and clinical research settings, these knockout cell lines are paramount for screening novel drug compounds and validating targets for cancer therapy. They also facilitate the identification of biomarkers for patient stratification in personalized medicine approaches. This unique biological model enables researchers to replicate the knockout condition consistently, thus generating reliable and reproducible data crucial for advancing our understanding of gene function.
Compared to alternative methods, such as transient transfection or RNA interference, DCAF4 Gene Knockout Cell Lines provide a stable and long-term solution for studying gene function in vivo. The knockout presence significantly enhances the specificity and penetrance of experimental outcomes, leading to more robust conclusions regarding the biological impacts of the gene in question.
Our commitment to excellence in the development of high-quality biological products underscores the value of DCAF4 Gene Knockout Cell Lines. Backed by a team of experienced scientists, our company leverages cutting-edge methodologies and extensive research to ensure that our products meet the highest standards of scientific integrity and utility. This positions our offerings as indispensable resources for researchers and clinicians aiming to drive innovation in genomic research and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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