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CTNND1 Knockout Cell Lines

Gene: CTNND1

Official Full Name: catenin delta 1provided by HGNC

Gene Summary: This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08646 CTNND1 Knockout cell line (HeLa) Human CTNND1 1:3~1:6 Negative Online Inquiry
KO08647 CTNND1 Knockout cell line (HCT 116) Human CTNND1 1:2~1:4 Negative Online Inquiry
KO08648 CTNND1 Knockout cell line (HEK293) Human CTNND1 1:3~1:6 Negative Online Inquiry
KO08649 CTNND1 Knockout cell line (A549) Human CTNND1 1:3~1:4 Negative Online Inquiry

Background

CTNND1 Gene Knockout Cell Lines are specialized cellular models engineered to exhibit a loss-of-function mutation in the CTNND1 gene, which encodes the protein catenin delta (δ-catenin). This product serves as a powerful research tool for investigating the role of CTNND1 in cellular processes such as cell adhesion, signal transduction, and the regulation of gene expression. The knockout mechanism is achieved through the application of CRISPR-Cas9 technology, which allows targeted editing of the genome, thus elucidating the gene’s function and its impact on various biological pathways.

The CTNND1 protein is known to play a critical role in tumorigenesis and cell motility, making these knockout cell lines particularly valuable for cancer research. By enabling researchers to study the effects of CTNND1 absence, these cell lines facilitate the exploration of underlying mechanisms of cancer progression and metastasis, as well as potential therapeutic targets. Furthermore, they can be employed in drug discovery and testing, helping to identify new compounds that might restore normal function or inhibit aberrant signaling pathways.

One of the key advantages of our CTNND1 Gene Knockout Cell Lines is their high specificity and reproducibility. Compared to traditional methods which may involve labor-intensive and time-consuming processes, the use of CRISPR technology guarantees precise genome editing with minimal off-target effects. This precision enhances the reliability of research outcomes, providing clear insights into the biological functions tied to CTNND1.

For researchers and clinicians, the availability of robust models such as the CTNND1 knockout cell lines accelerates the pace of scientific discovery, enabling a greater understanding of complex diseases. Our commitment to providing high-quality biological products is bolstered by our team of experienced scientists, ensuring that each product meets the highest standards of efficacy and reliability, ultimately empowering our users to make significant advancements in their respective fields.

Please note that all services are for research use only. Not intended for any clinical use.

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