Gene: CTDSPL2
Official Full Name: CTD small phosphatase like 2provided by HGNC
Gene Summary: Enables RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of BMP signaling pathway; positive regulation of protein export from nucleus; and protein dephosphorylation. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22481 | CTDSPL2 Knockout cell line (HeLa) | Human | CTDSPL2 | 1:3~1:6 | Negative | Online Inquiry |
KO22482 | CTDSPL2 Knockout cell line (HCT 116) | Human | CTDSPL2 | 1:2~1:4 | Negative | Online Inquiry |
KO22483 | CTDSPL2 Knockout cell line (HEK293) | Human | CTDSPL2 | 1:3~1:6 | Negative | Online Inquiry |
KO22484 | CTDSPL2 Knockout cell line (A549) | Human | CTDSPL2 | 1:3~1:4 | Negative | Online Inquiry |
CTDSPL2 Gene Knockout Cell Lines are innovative biological tools designed for in-depth functional studies of the CTDSPL2 gene, an essential component of cellular processes such as apoptosis and DNA damage response. These cell lines, developed using precise CRISPR/Cas9 gene-editing techniques, allow researchers to investigate the physiological roles of CTDSPL2 by providing a stark contrast between normal cellular function and those defined by the absence of this critical gene.
The primary mechanism behind CTDSPL2 gene knockout cell lines involves the targeted disruption of the CTDSPL2 gene, leading to a complete loss of its expression. This knockout approach enables thorough analyses of cellular pathways and phenotypes associated with CTDSPL2, including its impact on cell proliferation, survival, and response to various stressors. By utilizing these cell lines, scientists can elucidate the molecular mechanisms underpinning disease states, particularly in cancer and neurodegenerative disorders where CTDSPL2 plays a significant role.
The scientific importance of CTDSPL2 gene knockout cell lines lies in their versatile applications across both research and clinical settings. Researchers can employ these models to evaluate potential therapeutic targets, screen drug candidates, and develop gene therapy strategies. They also serve as a reference tool for functional genomics studies, enhancing our knowledge of gene regulation and interactions within complex biological systems.
Compared to traditional knockdown methods, such as RNA interference, the CTDSPL2 gene knockout cell lines offer stable and complete gene disruption, providing a more reliable and reproducible model for downstream applications. This specificity reduces experimental variability, allowing for clearer interpretation of results and more robust data.
Incorporating CTDSPL2 gene knockout cell lines into research protocols empowers scientists to achieve groundbreaking insights, drive innovation in therapeutic development, and enhance their understanding of fundamental biological processes. This product is invaluable to researchers and clinicians aiming to advance their work in gene function and the underlying mechanisms of diseases.
Our company is recognized for its cutting-edge approaches in genetic engineering and cell line development, ensuring that our products, including the CTDSPL2 gene knockout cell lines, are of the highest quality and designed to meet the rigorous demands of today’s scientific research. By providing tools that facilitate transformative discoveries, we reaffirm our commitment to supporting the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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