Home / CSTF2 Knockout Cell Lines

CSTF2 Knockout Cell Lines

Gene: Cstf2

Official Full Name: cleavage stimulation factor, 3' pre-RNA subunit 2provided by MGI

Gene Summary: Predicted to enable mRNA binding activity. Predicted to be involved in mRNA 3'-end processing. Predicted to be located in cleavage body. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is expressed in cerebral cortex intermediate zone; cerebral cortex ventricular layer; and cortical plate. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Orthologous to human CSTF2 (cleavage stimulation factor subunit 2). [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38366 CSTF2 Knockout cell line (HeLa) Human CSTF2 1:3~1:6 Negative Online Inquiry
KO38367 CSTF2 Knockout cell line (HCT 116) Human CSTF2 1:2~1:4 Negative Online Inquiry
KO38368 CSTF2 Knockout cell line (HEK293) Human CSTF2 1:3~1:6 Negative Online Inquiry
KO38369 CSTF2 Knockout cell line (A549) Human CSTF2 1:3~1:4 Negative Online Inquiry

Background

Cstf2 Gene Knockout Cell Lines are genetically modified cell lines designed to facilitate the study of the Cstf2 gene and its associated pathways. By employing CRISPR/Cas9 technology, these cell lines have been engineered to specifically disrupt the Cstf2 gene, allowing researchers to explore its role in RNA processing, transcription regulation, and cellular stress responses. This knockout model serves as a critical tool for investigating the molecular mechanisms underlying various diseases, particularly those linked with dysregulation of gene expression.

The primary function of Cstf2 involves its contribution to the cleavage and polyadenylation of pre-mRNAs, thereby impacting mRNA stability and translation. Disruption of this gene can lead to aberrant mRNA processing, illuminating the pathways that contribute to pathologies such as cancer, neurodegenerative disorders, and developmental anomalies. By utilizing these knockout cell lines, researchers can perform functional assays to delineate the effects of Cstf2 loss on gene expression patterns, cell cycle regulation, and apoptosis.

The scientific importance of Cstf2 Gene Knockout Cell Lines extends into both basic research and therapeutic investigations. In a clinical setting, understanding the implications of Cstf2 in disease can influence therapeutic strategies, potentially leading to novel interventions for disorders linked to mRNA processing anomalies. Compared to other models, these knockout cell lines offer precise genetic modifications that enable controlled studies, reducing unwanted variability present in primary cell cultures.

What sets our Cstf2 Gene Knockout Cell Lines apart from alternatives on the market is their validated reliability and extensive characterizations, which support reproducibility in research findings. Additionally, our commitment to quality ensures that these cell lines maintain robust growth and consistent behavior, crucial for experimental integrity.

Choosing Cstf2 Gene Knockout Cell Lines is a strategic investment for researchers and clinicians aiming to advance their understanding of genetic regulation and its impact on health. By leveraging our scientific background and expertise, we provide a superior product backed by extensive research and development in the field of molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.