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CSRNP1 Knockout Cell Lines

Gene: CSRNP1

Official Full Name: cysteine and serine rich nuclear protein 1provided by HGNC

Gene Summary: This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18504 CSRNP1 Knockout cell line (HeLa) Human CSRNP1 1:3~1:6 Negative Online Inquiry
KO18505 CSRNP1 Knockout cell line (HCT 116) Human CSRNP1 1:2~1:4 Negative Online Inquiry
KO18506 CSRNP1 Knockout cell line (HEK293) Human CSRNP1 1:3~1:6 Negative Online Inquiry
KO18507 CSRNP1 Knockout cell line (A549) Human CSRNP1 1:3~1:4 Negative Online Inquiry

Background

CSRNP1 Gene Knockout Cell Lines are advanced cellular models specifically engineered to eliminate the expression of the CSRNP1 gene, a critical player in various biological processes, including cellular differentiation and apoptosis. These knockout cell lines serve as invaluable tools for researchers aiming to decipher the functional roles of the CSRNP1 gene in different biological contexts.

The mechanism behind CSRNP1 Gene Knockout Cell Lines involves targeted gene editing techniques, such as CRISPR-Cas9, which effectively disrupt the CSRNP1 gene’s sequence. This disruption leads to a complete lack of the corresponding protein, allowing researchers to study the phenotypic changes associated with the absence of CSRNP1. By utilizing these cell lines, scientists can investigate the gene's involvement in key pathways, including those linked to cancer progression, neurodevelopmental disorders, and response to cellular stress.

The scientific importance of CSRNP1 Gene Knockout Cell Lines lies in their application across various research domains and clinical settings. They provide a unique platform for testing hypotheses about gene function, enabling insights into disease mechanisms and the discovery of potential therapeutic targets. Furthermore, these cell lines can facilitate drug screening processes, allowing for the evaluation of new therapeutic agents in a controlled environment.

One of the key advantages of our CSRNP1 Gene Knockout Cell Lines is their high specificity and reliability, which significantly enhance the robustness of experimental results compared to traditional methodologies. Unlike other knockout models that may exhibit off-target effects, our cell lines are meticulously validated to ensure consistent performance, providing researchers with confidence in their findings.

For researchers and clinicians, CSRNP1 Gene Knockout Cell Lines represent a significant advancement in cellular research tools, streamlining the investigation into gene function and contributing to the understanding of complex biological systems. Our company boasts a strong background in genetic engineering and cellular biology, ensuring that each product we deliver is of the highest quality and rigor. By choosing our CSRNP1 Gene Knockout Cell Lines, users can accelerate their research with a reliable and scientifically sound product that contributes meaningfully to the next generation of discoveries in health and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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