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CSPP1 Knockout Cell Lines

Gene: CSPP1

Official Full Name: centrosome and spindle pole associated protein 1provided by HGNC

Gene Summary: This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06464 CSPP1 Knockout cell line (HeLa) Human CSPP1 1:3~1:6 Negative Online Inquiry
KO06465 CSPP1 Knockout cell line (HCT 116) Human CSPP1 1:2~1:4 Negative Online Inquiry
KO06466 CSPP1 Knockout cell line (HEK293) Human CSPP1 1:3~1:6 Negative Online Inquiry
KO06467 CSPP1 Knockout cell line (A549) Human CSPP1 1:3~1:4 Negative Online Inquiry

Background

CSPP1 Gene Knockout Cell Lines are advanced cellular models specifically engineered to facilitate the study of the CSPP1 gene, which plays a critical role in cellular processes such as mitotic progression and cytoskeletal organization. These knockout cell lines are generated through precise gene-editing techniques, such as CRISPR/Cas9, to produce a loss-of-function phenotype, allowing researchers to observe the effects of CSPP1 depletion on cellular behavior and gene expression.

The key function of CSPP1 Gene Knockout Cell Lines lies in their ability to mimic pathological states by removing the encoding of the CSPP1 protein, thus enabling investigations into its role in diseases, including cancer and neurodevelopmental disorders. By utilizing these cell lines, scientists can explore the mechanisms by which CSPP1 influences cell proliferation, migration, and differentiation, providing insights that are crucial for developing targeted therapies and interventions.

The scientific importance of these cell lines extends to their applicability in both research and clinical settings. In research laboratories, they serve as an invaluable tool for elucidating the molecular pathways in which CSPP1 is involved, which may lead to breakthroughs in understanding tumor progression. Clinically, such models are essential for preclinical studies that assess the efficacy of novel drug candidates targeting CSPP1-related pathways.

Compared to traditional cell lines, CSPP1 Gene Knockout Cell Lines offer distinct advantages, including enhanced specificity in targeting CSPP1-related mechanisms and the potential for scalable production, ensuring consistency across experiments. This specificity helps to minimize off-target effects that often complicate interpretations in studies utilizing less engineered models.

For researchers and clinicians focused on gene function determination and pathway elucidation, CSPP1 Gene Knockout Cell Lines are not only a simple tool but a significant asset that can unlock new avenues for therapeutic interventions.

Our company's expertise in cutting-edge gene-editing technologies and commitment to providing high-quality biological products ensures that you receive reliable, reproducible results that can propel your research and clinical applications forward.

Please note that all services are for research use only. Not intended for any clinical use.

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