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CPT1B Knockout Cell Lines

Gene: CPT1B

Official Full Name: carnitine palmitoyltransferase 1Bprovided by HGNC

Gene Summary: The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07428 CPT1B Knockout cell line (HeLa) Human CPT1B 1:3~1:6 Negative Online Inquiry
KO07429 CPT1B Knockout cell line (HCT 116) Human CPT1B 1:2~1:4 Negative Online Inquiry
KO07430 CPT1B Knockout cell line (HEK293) Human CPT1B 1:3~1:6 Negative Online Inquiry
KO07431 CPT1B Knockout cell line (A549) Human CPT1B 1:3~1:4 Negative Online Inquiry

Background

CPT1B Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the study of the carnitine palmitoyltransferase 1B (CPT1B) gene's function in lipid metabolism and energy homeostasis. These cell lines are created through precise gene editing techniques to create knockout variants, allowing researchers to investigate the biological consequences of CPT1B deficiency in various cellular contexts. CPT1B plays a critical role in the transport of long-chain fatty acids into mitochondria, a key step in fatty acid oxidation, making these knockout models vital for elucidating metabolic pathways associated with energy expenditure and obesity-related disorders.

The key function of these cell lines lies in their ability to mimic conditions of CPT1B deficiency, which is essential for studying metabolic conditions such as insulin resistance, type 2 diabetes, and other lipid disorders. By utilizing these knockout cell lines, researchers can dissect the mechanisms by which CPT1B affects cellular metabolism, signaling pathways, and overall cell health, providing valuable insights into potential therapeutic targets for metabolic diseases.

Significantly, CPT1B Gene Knockout Cell Lines offer several advantages over traditional experimental models, such as the ability to perform high-throughput screening for drug discoveries, and the potential to yield more reproducible data while minimizing variability linked to genetic differences in standard cell lines. This specificity makes them exceptionally valuable to researchers focused on metabolic research and drug development.

For clinicians and researchers alike, the implications of utilizing CPT1B Gene Knockout Cell Lines extend beyond basic research; they present a critical tool for advancing our understanding of metabolic syndromes and the development of novel therapies. These cell lines are particularly appealing for studies aimed at identifying mechanisms behind metabolic disorders and how they could be targeted for intervention.

Our company specializes in providing high-quality biological products that meet rigorous standards for research applicability. With an expert team dedicated to the innovation of genetic models, we ensure that our CPT1B Gene Knockout Cell Lines are consistently of the highest quality, empowering researchers to drive forward their explorations in metabolic health with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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