Gene: CMAS
Official Full Name: cytidine monophosphate N-acetylneuraminic acid synthetaseprovided by HGNC
Gene Summary: This gene encodes an enzyme that converts N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc). This process is important in the formation of sialylated glycoprotein and glycolipids. This modification plays a role in cell-cell communications and immune responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18650 | CMAS Knockout cell line (HeLa) | Human | CMAS | 1:3~1:6 | Negative | Online Inquiry |
KO18651 | CMAS Knockout cell line (HCT 116) | Human | CMAS | 1:2~1:4 | Negative | Online Inquiry |
KO18652 | CMAS Knockout cell line (HEK293) | Human | CMAS | 1:3~1:6 | Negative | Online Inquiry |
KO18653 | CMAS Knockout cell line (A549) | Human | CMAS | 1:3~1:4 | Negative | Online Inquiry |
CMAS Gene Knockout Cell Lines are specifically engineered cell lines that have undergone targeted genetic modifications to disrupt the expression of the CMAS gene. This gene is pivotal in multiple biological processes, including glycosylation pathways, which play significant roles in cellular structure and signaling. By employing CRISPR/Cas9 technology, researchers can precisely create knockout models that enable the study of CMAS function and its implications in various diseases, particularly those involving glycan biosynthesis.
The primary function of CMAS Gene Knockout Cell Lines is to facilitate the elucidation of the molecular mechanisms behind CMAS-related pathways and their involvement in cellular responses. These cell lines allow scientists to observe alterations in cellular behavior, metabolism, and signaling cascades that result from the absence of functional CMAS, providing essential insights into its role in health and disease states.
In both research and clinical settings, these knockout cell lines serve as invaluable tools for studying pathological conditions such as cancer and metabolic disorders, where altered glycosylation is a hallmark. Additionally, they can aid in drug development efforts by serving as models for testing therapeutic compounds aimed at restoring normal function in the glycosylation pathways disrupted by CMAS deficiencies.
What sets CMAS Gene Knockout Cell Lines apart from traditional models is their precision and reliance on cutting-edge genetic modification technology, ensuring high specificity and reproducibility of experimental results. These models eliminate the variability often seen in natural mutations, thereby providing a reliable platform for researchers pursuing rigorous scientific inquiries.
For researchers and clinicians, the value of utilizing CMAS Gene Knockout Cell Lines lies in their ability to streamline experiments, reduce time taken for preliminary research, and enhance the robustness of findings. The exacting nature of these models empowers users to draw clearer and more reliable conclusions, ultimately advancing the field of genetic research.
Our company prides itself on delivering high-quality, state-of-the-art biological products. With a commitment to supporting scientific advancement, we provide invaluable tools like the CMAS Gene Knockout Cell Lines to enhance research capabilities and facilitate breakthroughs in understanding genetic functions and implications in human health.
Please note that all services are for research use only. Not intended for any clinical use.
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