Gene: CLTCL1
Official Full Name: clathrin heavy chain like 1provided by HGNC
Gene Summary: This gene is a member of the clathrin heavy chain family and encodes a major protein of the polyhedral coat of coated pits and vesicles. Chromosomal aberrations involving this gene are associated with meningioma, DiGeorge syndrome, and velo-cardio-facial syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04816 | CLTCL1 Knockout cell line (HeLa) | Human | CLTCL1 | 1:3~1:6 | Negative | Online Inquiry |
KO04817 | CLTCL1 Knockout cell line (HCT 116) | Human | CLTCL1 | 1:2~1:4 | Negative | Online Inquiry |
KO04818 | CLTCL1 Knockout cell line (HEK293) | Human | CLTCL1 | 1:3~1:6 | Negative | Online Inquiry |
KO04819 | CLTCL1 Knockout cell line (A549) | Human | CLTCL1 | 1:3~1:4 | Negative | Online Inquiry |
CLTCL1 Gene Knockout Cell Lines are specialized cellular models created to facilitate the investigation of the CLTCL1 gene, known for its role in cellular processes such as apoptosis and cytoskeletal dynamics. These cell lines are engineered using CRISPR-Cas9 technology to achieve precise and permanent disruption of the CLTCL1 gene, providing researchers with a powerful tool to elucidate the gene's functional implications in various biological pathways.
The key mechanism of the CLTCL1 Gene Knockout Cell Lines lies in the targeted ablation of the CLTCL1 protein, which is implicated in processes such as cellular signaling and membrane trafficking. By studying these knockout variants, scientists can observe phenotypic changes and disruptions in cellular behavior that result from the loss of CLTCL1 function. This direct approach allows for a clearer understanding of its role in health and disease, particularly in conditions where cytoskeletal integrity and cellular communication are vital.
Scientifically, these knockout cell lines hold significant importance in both research and clinical settings, serving as invaluable models for studies related to cancer, neurodegenerative disorders, and other diseases where CLTCL1 dysregulation may be a contributing factor. They enable high-throughput screening of potential therapeutic compounds and provide a platform for gene function studies, enhancing the understanding of gene-disease relationships.
Unlike traditional cell lines, CLTCL1 Gene Knockout Cell Lines offer enhanced specificity and reliability, reducing potential confounding variables and generating more reproducible results. Their precise genetic modification ensures that researchers can draw more accurate correlations between genetic alteration and biological consequence, making them superior to conventional wild-type or poorly characterized cell models.
For researchers and clinicians seeking to unravel the complexities of gene function and its implication in disease, CLTCL1 Gene Knockout Cell Lines represent a valuable asset. They provide clarity in experimental outcomes and contribute to the advancement of precision medicine.
At [Your Company Name], we pride ourselves on delivering high-quality biological products tailored to meet the rigorous demands of modern scientific inquiry. Our expertise in gene editing and cell line development ensures that our offerings are not only innovative but also at the forefront of biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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