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CLASP1 Knockout Cell Lines

Gene: CLASP1

Official Full Name: cytoplasmic linker associated protein 1provided by HGNC

Gene Summary: CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170; MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle (Maiato et al., 2003 [PubMed 12837247]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18676 CLASP1 Knockout cell line (HeLa) Human CLASP1 1:3~1:6 Negative Online Inquiry
KO18677 CLASP1 Knockout cell line (HCT 116) Human CLASP1 1:2~1:4 Negative Online Inquiry
KO18678 CLASP1 Knockout cell line (HEK293) Human CLASP1 1:3~1:6 Negative Online Inquiry
KO18679 CLASP1 Knockout cell line (A549) Human CLASP1 1:3~1:4 Negative Online Inquiry

Background

CLASP1 Gene Knockout Cell Lines are genetically modified cellular models derived from established mammalian cell lines, where the CLASP1 gene has been inactivated through targeted genome editing techniques such as CRISPR/Cas9. This product is vital for researchers investigating the multifaceted roles of CLASP1 in cellular processes, particularly in microtubule stabilization, cell division, and intracellular transport mechanisms.

The primary function of the CLASP1 gene involves the regulation of the cytoskeletal dynamics necessary for proper cellular architecture and function. By knocking out the CLASP1 gene, these cell lines allow for the direct investigation of the physiological and pathological implications of CLASP1 disruption. Researchers can study phenotypic changes, assess impact on cell signaling pathways, and explore the correlation between CLASP1 activity and various diseases, including cancer and neurodegenerative disorders.

The scientific importance of these knockout cell lines cannot be overstated; they serve as essential tools in basic biological research, drug discovery, and therapeutic development. Their applications extend to high-throughput screening for potential pharmaceutical agents targeting microtubule-associated processes.

Compared to traditional cell lines that express CLASP1, our specialized knockout lines present a unique opportunity to dissect the gene’s role effortlessly. This specificity aids in reducing background noise in experiments and allows for clearer interpretations of data through controlled experimental designs.

For researchers and clinicians aiming to contribute to groundbreaking studies or develop new therapeutic strategies, CLASP1 Gene Knockout Cell Lines offer unparalleled value as a robust platform for functional genomics. By utilizing our expertly developed cell lines, users can leverage our dedication to quality and innovation, positioning themselves at the forefront of biomedical research.

Our company specializes in providing precise and reliable biological products designed to empower scientific inquiries. With our extensive experience in genetic engineering and cell line development, we are committed to supporting advancements in biological research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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