Gene: CHST9
Official Full Name: carbohydrate sulfotransferase 9provided by HGNC
Gene Summary: The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25470 | CHST9 Knockout cell line (HEK293) | Human | CHST9 | 1:3~1:6 | Negative | Online Inquiry |
CHST9 Gene Knockout Cell Lines are sophisticated biological tools specifically engineered to eliminate the expression of the CHST9 gene, which encodes for the carbohydrate sulfotransferase enzyme involved in glycosaminoglycan biosynthesis. These cell lines facilitate profound investigations into the role of CHST9 in cellular processes, including development, differentiation, and pathogenesis. By employing CRISPR/Cas9 technology, each cell line ensures precise gene editing, providing a reliable model for understanding the functional consequences of CHST9 absence.
Key functions of the CHST9 Gene Knockout Cell Lines revolve around dissecting the molecular pathways influenced by glycosaminoglycans. The knockout capability allows researchers to study the resultant phenotypic changes and cellular behaviors, enabling them to ascertain the gene’s involvement in various biological contexts such as cancer progression, immunological responses, and tissue regeneration. This specificity not only advances fundamental research but also paves the way for therapeutic innovations targeting CHST9-related disorders.
The scientific importance of these cell lines is underscored by their application in both bench research and clinical settings. They serve as essential platforms for drug discovery and development, particularly in understanding drug mechanisms that target glycosaminoglycan interactions, thereby influencing therapeutic strategies in oncology and regenerative medicine.
What distinguishes our CHST9 Gene Knockout Cell Lines from alternative models is their high fidelity and ease of use, as well as access to comprehensive customer support throughout the research lifecycle. Furthermore, our product adheres to stringent quality controls, ensuring reproducibility and reliability in experimental outcomes, essential for producing publishable data and facilitating grant applications.
For researchers and clinicians, the value of incorporating CHST9 Gene Knockout Cell Lines into experimental protocols cannot be overstated; these tools not only enhance the understanding of gene function but also bolster innovative approaches in personalized medicine and gene therapy.
Our company prides itself on its robust expertise in creating cutting-edge biological products, underpinned by a commitment to advancing scientific discovery. We provide exceptional resources to ensure that our products meet the evolving needs of the research community, aligning science with transformative possibilities.
Please note that all services are for research use only. Not intended for any clinical use.
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