Gene: CHPF2
Official Full Name: chondroitin polymerizing factor 2provided by HGNC
Gene Summary: Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Predicted to be involved in chondroitin sulfate biosynthetic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21706 | CHPF2 Knockout cell line (HeLa) | Human | CHPF2 | 1:3~1:6 | Negative | Online Inquiry |
KO21707 | CHPF2 Knockout cell line (HCT 116) | Human | CHPF2 | 1:2~1:4 | Negative | Online Inquiry |
KO21708 | CHPF2 Knockout cell line (HEK293) | Human | CHPF2 | 1:3~1:6 | Negative | Online Inquiry |
KO21709 | CHPF2 Knockout cell line (A549) | Human | CHPF2 | 1:3~1:4 | Negative | Online Inquiry |
CHPF2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the CHPF2 gene, a critical component involved in the biosynthesis of chondroitin sulfate proteoglycans. These cell lines serve as invaluable tools for understanding the physiological and pathological roles of CHPF2 in cellular behavior, signaling pathways, and extracellular matrix composition. By manipulating the expression of this gene, researchers can investigate the impact of CHPF2 deficiency on cell proliferation, differentiation, and various metabolic processes.
The mechanism of action behind these knockout cell lines relies on CRISPR/Cas9 gene-editing technology, which enables precise alterations at the genomic level. By creating a loss-of-function model, researchers can elucidate the gene's contribution to numerous cellular functions and its implications in diseases such as cancer, musculoskeletal disorders, and neurodegenerative conditions. The CHPF2 Gene Knockout Cell Lines allow for versatile experimental designs, including drug response assays, gene expression studies, and modeling of disease phenotypes, making them essential for both basic and translational research.
In comparison to other knockout models, the CHPF2 Gene Knockout Cell Lines represent a targeted approach with a high specificity and efficiency of gene disruption, providing more reliable insights than traditional gene silencing methods. Their unique capability to mimic disease states accurately offers a strategic advantage for researchers aiming to develop therapeutics and gain deeper insights into gene function.
For researchers and clinicians, utilizing CHPF2 Gene Knockout Cell Lines means accessing a robust platform that drives innovation in cell biology and therapeutic development. Their role in advancing our understanding of proteoglycan metabolism is critical for making strides in targeted therapies and personalized medicine.
Our company specializes in delivering high-quality biological products, backed by extensive expertise in gene editing and cell line development. We are committed to supporting the scientific community by providing tools that enhance research capabilities and lead to novel discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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