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CHD6 Knockout Cell Lines

Gene: CHD6

Official Full Name: chromodomain helicase DNA binding protein 6provided by HGNC

Gene Summary: This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25113 CHD6 Knockout cell line (HeLa) Human CHD6 1:3~1:6 Negative Online Inquiry
KO25114 CHD6 Knockout cell line (HCT 116) Human CHD6 1:2~1:4 Negative Online Inquiry
KO25115 CHD6 Knockout cell line (HEK293) Human CHD6 1:3~1:6 Negative Online Inquiry
KO25116 CHD6 Knockout cell line (A549) Human CHD6 1:3~1:4 Negative Online Inquiry

Background

CHD6 Gene Knockout Cell Lines are specialized mammalian cell lines that feature the targeted disruption of the CHD6 gene, which is known to play a crucial role in chromatin remodeling, gene expression regulation, and DNA repair mechanisms. By utilizing advanced CRISPR-Cas9 gene editing technology, these cell lines enable researchers to investigate the functional consequences of CHD6 deficiency, thereby providing deep insights into its involvement in various biological processes and disease states.

The key function of the CHD6 Gene Knockout Cell Lines lies in their ability to serve as a model for studying the gene's role in cellular processes such as cell cycle regulation, apoptosis, and cellular response to DNA damage. The knockout of CHD6 protein allows for the elucidation of downstream signaling pathways and gene expression alterations, facilitating a better understanding of its contributions to conditions like cancer and genetic disorders. This rational approach elucidates how disruptions in chromatin remodeling can lead to various pathologies, providing a platform for targeted therapeutic research.

Scientifically, these cell lines are paramount in both basic and applied research settings, including oncology, neurobiology, and developmental biology. They allow for the exploration of mechanisms at the molecular level, making them invaluable tools for drug discovery and the development of therapeutic interventions. Researchers can conduct various assays to assess cellular responses to different treatments, thus bridging the gap between basic research and clinical applications.

A significant advantage of CHD6 Gene Knockout Cell Lines is their specificity and precision as a research tool. Unlike traditional cell lines, which may exhibit varying levels of gene expression, these knockout lines provide a consistent model devoid of the CHD6 function. This specificity enhances reproducibility in experiments and the reliability of results, which is crucial for advancing scientific knowledge.

For researchers and clinicians aiming to understand the multifaceted roles of CHD6 in health and disease, these knockout cell lines are an indispensable resource. They offer unparalleled insights that can lead to breakthroughs in therapeutic strategies and personalized medicine.

At [Your Company Name], we pride ourselves on our cutting-edge gene editing technologies and our commitment to providing high-quality biological products. Our expertise in cellular models ensures that researchers have access to the best tools for advancing scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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