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CGRRF1 Knockout Cell Lines

Gene: CGRRF1

Official Full Name: cell growth regulator with ring finger domain 1provided by HGNC

Gene Summary: Predicted to enable metal ion binding activity. Predicted to be involved in negative regulation of cell growth. Located in endoplasmic reticulum and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31629 CGRRF1 Knockout cell line (HeLa) Human CGRRF1 1:3~1:6 Negative Online Inquiry
KO31630 CGRRF1 Knockout cell line (HCT 116) Human CGRRF1 1:2~1:4 Negative Online Inquiry
KO31631 CGRRF1 Knockout cell line (HEK293) Human CGRRF1 1:3~1:6 Negative Online Inquiry
KO31632 CGRRF1 Knockout cell line (A549) Human CGRRF1 1:3~1:4 Negative Online Inquiry

Background

CGRRF1 gene knockout cell lines are specialized biological tools designed to aid researchers in elucidating the functional role of the CGRRF1 gene. This gene is implicated in various physiological processes, making its knockout an invaluable resource for studying gene function, signaling pathways, and cellular responses to environmental stimuli. Utilizing CRISPR-Cas9 technology, these cell lines exhibit a precise and efficient disruption of the CGRRF1 gene, leading to a loss of function that can be thoroughly investigated across different cellular contexts.

The key function of the CGRRF1 knockout is to serve as a model for assessing the downstream effects of CGRRF1 deficiency. By investigating changes in cellular behaviors, such as proliferation, migration, and differentiation, researchers can better understand the gene's contributions to normal physiology and disease states. Studies using these knockout cell lines can provide critical insights into oncogenesis, neurodegeneration, and metabolic disorders, thus enhancing their scientific importance in both research and clinical applications.

Compared to traditional methods for gene silencing, such as RNA interference, CRISPR-Cas9 gene editing offers a more stable and heritable modification, making CGRRF1 knockout cell lines superior in terms of reliability and reproducibility. Additionally, these cell lines can be readily employed in high-throughput screening assays, facilitating accelerated drug discovery and validation efforts.

For researchers and clinicians, the ability to study the specific pathways and mechanisms associated with CGRRF1 deficiency underscores its immense value in advancing our understanding of gene function in health and disease. By employing these cell lines, users can derive meaningful biological insights that may contribute to the development of targeted therapies.

At our company, we pride ourselves on providing high-quality, customizable gene knockout models backed by expert knowledge in the field of molecular biology. Our commitment to scientific excellence ensures that our CGRRF1 gene knockout cell lines will significantly enhance your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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