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CFAP90 Knockout Cell Lines

Gene: CFAP90

Official Full Name: cilia and flagella associated protein 90provided by HGNC

Gene Summary: Predicted to be involved in flagellated sperm motility. Located in axoneme and ciliary basal body. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18786 CFAP90 Knockout cell line (HEK293) Human CFAP90 1:3~1:6 Negative Online Inquiry

Background

CFAP90 Gene Knockout Cell Lines are specially engineered cellular models in which the CFAP90 gene has been systematically inactivated, allowing researchers to investigate the gene's biological role and its contributions to various cellular processes. This product facilitates the study of the implications of CFAP90 in motility, cilia formation, and related disorders, thereby providing a valuable tool for dissecting complex biological pathways.

The functionality of CFAP90 Gene Knockout Cell Lines lies in their ability to mimic cellular conditions where CFAP90 is absent or dysfunctional. The knockout mechanism employs CRISPR/Cas9 technology, which ensures precise gene editing, creating a reliable model for studying gene function, phenotypic variation, and underlying molecular mechanisms. By comparing these knockout cells with wild-type counterparts, researchers can identify changes in cellular behaviors, signaling pathways, and protein expression profiles that are directly attributable to CFAP90's absence.

The scientific significance of CFAP90 Gene Knockout Cell Lines extends into both fundamental research and clinical applications. They serve as a powerful platform for researching ciliopathies, reproductive biology, and cardiovascular diseases associated with ciliary dysfunction. Furthermore, these cell lines could help in drug discovery and the development of therapeutic strategies targeting cilia-related disorders.

What sets CFAP90 Gene Knockout Cell Lines apart from traditional models is their high specificity and reproducibility. Unlike non-specific knockdown approaches using siRNA, this knockout model allows for a complete loss-of-function state of the gene, leading to more robust and reliable data. Additionally, their adaptability to various assay formats makes them ideal for high-throughput screening and other experimental setups.

For researchers and clinicians committed to advancing their understanding of genetic influences in human health, investing in CFAP90 Gene Knockout Cell Lines is invaluable. These cell lines not only enhance research capabilities but also pave the way for potential therapeutic innovations. Our company specializes in providing high-quality biological products, including advanced gene editing tools and customizable cell lines, underscoring our commitment to empowering scientific discovery and improving clinical outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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