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CECR2 Knockout Cell Lines

Gene: CECR2

Official Full Name: CECR2 histone acetyl-lysine readerprovided by HGNC

Gene Summary: This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27592 CECR2 Knockout cell line (HCT 116) Human CECR2 1:2~1:4 Negative Online Inquiry
KO27593 CECR2 Knockout cell line (HEK293) Human CECR2 1:3~1:6 Negative Online Inquiry

Background

CECR2 Gene Knockout Cell Lines are genetically engineered cell lines designed to facilitate the study of the CECR2 gene’s role in various biological processes and disease mechanisms. These cell lines are created through the targeted deletion of the CECR2 (Cat-eye syndrome critical region protein 2) gene, utilizing advanced CRISPR/Cas9 gene-editing technology. By specifically knocking out CECR2, researchers can investigate the gene's functions and its contributions to cellular behavior and differentiation.

The primary function of CECR2 is associated with chromatin remodeling and gene regulation, impacting crucial physiological processes, including development and immune responses. Through the use of these knockout cell lines, scientists can elucidate the signaling pathways and molecular interactions influenced by CECR2, providing insights into its role in conditions such as Cat-eye syndrome and other genetic disorders. The detailed understanding of CECR2 function can facilitate the identification of potential therapeutic targets and biomarkers for diagnostic purposes.

The scientific importance of CECR2 Gene Knockout Cell Lines extends to both research and clinical applications. They serve as invaluable tools for studying the genetic underpinning of diseases, enabling high-throughput screening assays, drug discovery, and the evaluation of therapeutic interventions. Researchers benefit from robust data regarding CECR2's interactions, helping to create a more comprehensive understanding of its impact on human health.

Compared to alternative models such as wild-type or non-targeted cell lines, CECR2 Gene Knockout Cell Lines offer the unique advantage of clarity in gene function studies. Researchers can observe the phenotypic effects and cellular responses that arise specifically from the absence of CECR2, thus improving the reliability of their findings.

In summary, CECR2 Gene Knockout Cell Lines not only enhance the capability of researchers and clinicians to explore genetic functions but also open new avenues for translational research aimed at understanding and treating genetic disorders. Our company brings together decades of expertise in genetic engineering and cell line development, ensuring that our products are of the highest quality and precision, enabling breakthroughs in biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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