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CDKL1 Knockout Cell Lines

Gene: CDKL1

Official Full Name: cyclin dependent kinase like 1provided by HGNC

Gene Summary: This gene product is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. [provided by RefSeq, Nov 2018]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07007 CDKL1 Knockout cell line (HeLa) Human CDKL1 1:3~1:6 Negative Online Inquiry
KO07008 CDKL1 Knockout cell line (HCT 116) Human CDKL1 1:2~1:4 Negative Online Inquiry
KO07009 CDKL1 Knockout cell line (HEK293) Human CDKL1 1:3~1:6 Negative Online Inquiry
KO07010 CDKL1 Knockout cell line (A549) Human CDKL1 1:3~1:4 Negative Online Inquiry

Background

CDKL1 Gene Knockout Cell Lines are specially engineered cellular models created to enable the study of the cyclin-dependent kinase-like 1 (CDKL1) gene, a crucial regulator involved in various aspects of cell cycle progression and neuronal function. These cell lines are developed using CRISPR/Cas9 technology, which facilitates precise gene editing to effectively disrupt the CDKL1 gene, allowing researchers to explore the downstream effects of CDKL1 deficiency on cellular mechanisms.

The primary function of CDKL1 is to modulate the phosphorylation of key substrates involved in regulating the cell cycle and neuronal growth. By knocking out this gene, researchers can investigate alterations in cell proliferation, differentiation, and signal transduction pathways, providing critical insights into its biological roles and the potential implications in diseases such as cancer and neurodegenerative disorders.

The scientific importance of these knockout cell lines is evident in their wide-ranging applications in both research and clinical settings. They serve as valuable tools for studying cell biology, drug screening, and the validation of therapeutic targets. Understanding the function of CDKL1 can lead to advancements in treatment strategies for conditions associated with aberrant cell cycle regulation and neuronal dysfunction.

Compared to alternative models, our CDKL1 Gene Knockout Cell Lines offer a host of advantages, including high specificity due to the precision of CRISPR technology and the ability to be tailored to various cell types. Furthermore, these cell lines provide a reproducible and consistent platform for experimentation, minimizing variability and enhancing data reliability.

For researchers and clinicians, the value of our CDKL1 Gene Knockout Cell Lines lies in their potential to illuminate the mechanisms by which CDKL1 influences crucial biological processes. With the combination of robust engineering and extensive functional characterization, these cell lines are an indispensable resource for advancing our understanding of cellular dynamics.

As a leading provider of innovative biological products, our company is committed to delivering high-quality research tools that empower scientific inquiry. We leverage our expertise in gene editing and cell line development to support researchers in their quest to unlock the complexities of gene function, ensuring that you have the best resources at your disposal for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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