Gene: CDC42EP2
Official Full Name: CDC42 effector protein 2provided by HGNC
Gene Summary: CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31876 | CDC42EP2 Knockout cell line (HeLa) | Human | CDC42EP2 | 1:3~1:6 | Negative | Online Inquiry |
KO31877 | CDC42EP2 Knockout cell line (HCT 116) | Human | CDC42EP2 | 1:2~1:4 | Negative | Online Inquiry |
KO31878 | CDC42EP2 Knockout cell line (HEK293) | Human | CDC42EP2 | 1:3~1:6 | Negative | Online Inquiry |
KO31879 | CDC42EP2 Knockout cell line (A549) | Human | CDC42EP2 | 1:3~1:4 | Negative | Online Inquiry |
CDC42EP2 Gene Knockout Cell Lines are specialized cellular models designed to study the role of the CDC42EP2 gene in various biological processes and diseases. These cell lines have been engineered through advanced CRISPR/Cas9 gene-editing technology to specifically knockout the CDC42EP2 gene, allowing researchers to investigate its function in cellular signaling pathways, cytoskeletal dynamics, and tumorigenesis.
The primary mechanism of these knockout cell lines involves the complete ablation of CDC42EP2, which is known to play a critical role in controlling cell proliferation, migration, and adhesion through its interaction with CDC42, a member of the Rho family of GTPases. By specifically disrupting this gene, researchers can elucidate the downstream effects on cellular behavior, contributing valuable insights into how dysregulation may lead to pathological conditions, particularly in cancers where CDC42EP2 expression is often altered.
In scientific and clinical research contexts, the importance of CDC42EP2 gene knockout cell lines cannot be overstated. They serve as fundamental tools for examining the gene's contribution to cancer biology, neurobiology, and tissue regeneration, facilitating the development of targeted therapies. Moreover, their capacity to mimic disease conditions makes them invaluable for drug discovery and testing, ultimately leading to innovations in patient care.
What sets our CDC42EP2 Gene Knockout Cell Lines apart from alternatives is our commitment to high-quality standardization and robust validation. Each cell line is thoroughly characterized and undergoes comprehensive functional assays to ensure reproducibility and reliability in results. Furthermore, these cell lines are derived from various primary cell types, enabling diverse experimental applications across multiple research fields.
In summary, our CDC42EP2 Gene Knockout Cell Lines offer exceptional value for researchers and clinicians seeking to explore the intricacies of gene function and its implications in disease. With a focus on quality, innovation, and utility, our company prides itself on providing superior biological research products that empower scientific discovery and advance healthcare solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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