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CDC42BPG Knockout Cell Lines

Gene: CDC42BPG

Official Full Name: CDC42 binding protein kinase gammaprovided by HGNC

Gene Summary: Enables ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Involved in protein phosphorylation. Located in cell leading edge; centriolar satellite; and cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18885 CDC42BPG Knockout cell line (HeLa) Human CDC42BPG 1:3~1:6 Negative Online Inquiry
KO18886 CDC42BPG Knockout cell line (HCT 116) Human CDC42BPG 1:2~1:4 Negative Online Inquiry
KO18887 CDC42BPG Knockout cell line (HEK293) Human CDC42BPG 1:3~1:6 Negative Online Inquiry

Background

CDC42BPG Gene Knockout Cell Lines are engineered cellular models specifically designed to investigate the functional role of the CDC42BPG gene, which encodes a protein implicated in various cellular processes, including cell migration, cytoskeletal dynamics, and tumorigenesis. This gene plays a critical part in the signaling pathways that govern cell shape and movement, making its study essential for understanding many cellular functions and diseases.

These knockout cell lines effectively remove the functional expression of the CDC42BPG gene, allowing researchers to explore the consequences of its absence on cellular behavior and signaling mechanisms. The knockout strategy involves CRISPR/Cas9 technology, ensuring precise and efficient gene disruption. As a result, researchers can elucidate the gene's role in cellular pathways, thereby shedding light on important pathological processes linked to cancer and other diseases.

The scientific importance of CDC42BPG Gene Knockout Cell Lines extends to research applications, where they are invaluable tools in cancer biology, pharmacology, and developmental studies. By providing a definitive model for understanding the gene's contributions to malignant transformation and progression, these cell lines aid in the development of targeted therapies and the identification of potential biomarkers.

Compared to alternative cell lines, these knockout models are uniquely advantageous due to their specificity and the precision of gene editing. This specificity allows for more accurate interpretations of experimental results, leading to higher confidence in data derived from these models. Furthermore, researchers benefit from the ability to conduct both in vitro and in vivo studies, enhancing the translational potential of their findings.

For researchers and clinicians, the CDC42BPG Gene Knockout Cell Lines represent a significant advancement in the toolkit available for cellular and molecular investigations. They empower users to achieve breakthroughs in their studies related to cell signaling and cancer biology. Our company prides itself on its expertise in gene editing technologies, providing high-quality biological products that support innovative research and therapeutic developments.

Please note that all services are for research use only. Not intended for any clinical use.

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