Gene: CCNI
Official Full Name: cyclin Iprovided by HGNC
Gene Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin shows the highest similarity with cyclin G. The transcript of this gene was found to be expressed constantly during cell cycle progression. [provided by RefSeq, Jan 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03975 | CCNI Knockout cell line (HeLa) | Human | CCNI | 1:3~1:6 | Negative | Online Inquiry |
KO03976 | CCNI Knockout cell line (HCT 116) | Human | CCNI | 1:2~1:4 | Negative | Online Inquiry |
KO03977 | CCNI Knockout cell line (HEK293) | Human | CCNI | 1:3~1:6 | Negative | Online Inquiry |
KO03978 | CCNI Knockout cell line (A549) | Human | CCNI | 1:3~1:4 | Negative | Online Inquiry |
CCNI Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the CCNI gene's functions by completely disrupting its expression. This innovative product utilizes CRISPR/Cas9 technology to achieve precise genetic modifications, allowing researchers to delineate the biological role of CCNI in various cellular processes. By generating knockout cell lines, scientists can explore the implications of CCNI dysregulation in pathologies such as cancer, neurodegenerative diseases, and metabolic disorders.
The primary function of the CCNI Gene Knockout Cell Lines is to serve as a valuable tool for functional genomics studies. The knockout mechanism involves introducing targeted double-strand breaks in the genomic DNA, followed by non-homologous end joining, which results in gene disruption. This precise approach ensures that researchers can confidently assess the phenotype associated with the loss of CCNI expression, thus contributing significantly to our understanding of gene function and cellular behavior.
The scientific importance of these cell lines is profound; they represent indispensable models for elucidating the pathways and mechanisms in which CCNI is involved. Their applications extend to both in vitro assays and pharmacological testing, making them crucial for drug development and therapeutic research. Furthermore, these cell lines can be integrated into high-throughput screening platforms, paving the way for the identification of potential drug targets or biomarkers.
What sets CCNI Gene Knockout Cell Lines apart from alternative models is their comprehensive validation and the consistency of results. Unlike other freely available cell lines, our products are rigorously characterized for performance and phenotype, ensuring reliability in experimental outcomes. They also come with detailed documentation, including growth conditions and experimental guidelines, facilitating seamless integration into existing research workflows.
For researchers and clinicians focused on advancing knowledge in cellular mechanisms and disease models, CCNI Gene Knockout Cell Lines present an invaluable resource. Their ability to directly assess gene function provides insights that are crucial for translational research, ultimately leading to novel therapeutic strategies.
As a leader in the field of biological research products, our company is committed to providing high-quality, genetically-engineered cell lines that empower scientific discovery. Our expertise in gene editing and cell line development ensures that customers receive not only exceptional products but also expert guidance and support for their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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