Gene: CCDC18
Official Full Name: coiled-coil domain containing 18provided by HGNC
Gene Summary: Located in centriolar satellite. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19034 | CCDC18 Knockout cell line (HeLa) | Human | CCDC18 | 1:3~1:6 | Negative | Online Inquiry |
KO19035 | CCDC18 Knockout cell line (HCT 116) | Human | CCDC18 | 1:2~1:4 | Negative | Online Inquiry |
KO19036 | CCDC18 Knockout cell line (HEK293) | Human | CCDC18 | 1:3~1:6 | Negative | Online Inquiry |
KO19037 | CCDC18 Knockout cell line (A549) | Human | CCDC18 | 1:3~1:4 | Negative | Online Inquiry |
CCDC18 Gene Knockout Cell Lines are a genetically engineered model system that specifically lacks the CCDC18 gene, which encodes a protein involved in critical cellular processes, including cell division, cytoskeletal organization, and potentially in the modulation of gene expression. These cell lines serve as invaluable tools for researchers aiming to elucidate the functional roles and biological significance of the CCDC18 gene in various physiological and pathological contexts.
The key function of the CCDC18 Gene Knockout Cell Lines lies in their ability to mimic loss-of-function scenarios. They provide a controlled environment to assess the impact of CCDC18 deletion on cellular behavior, signaling pathways, and gene regulation. By utilizing CRISPR/Cas9 technology or other gene-editing tools, these cell lines ensure precise and stable knockout of the CCDC18 gene, allowing for comprehensive investigations into the cellular and molecular mechanisms underlying diseases, especially those related to cancer and developmental disorders.
In scientific research, these knockout cell lines have significant applications, ranging from basic biology studies to drug discovery and development. Clinically, they can inform therapeutic strategies by identifying potential targets for intervention and enhancing our understanding of tumorigenesis, resistance mechanisms, and drug efficacy in cancer treatment.
When compared to traditional cell models that may harbor extensive genetic variations, CCDC18 Gene Knockout Cell Lines stand out due to their specificity and the reproducibility of results. This precision allows for more reliable data, crucial for advancing translational research. Additionally, the availability of a model that definitively lacks CCDC18 enables researchers to isolate the effects of this gene without confounding factors associated with wild-type cells.
The value of CCDC18 Gene Knockout Cell Lines to researchers and clinicians lies in their ability to provide clear insights and innovative approaches to explore complex biological questions, which can lead to breakthroughs in personalized medicine and therapeutic interventions.
At [Your Company Name], we pride ourselves on our commitment to providing high-quality, precise biological tools tailored for rigorous research applications, furthering the advancement of biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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