Gene: CBR4
Official Full Name: carbonyl reductase 4provided by HGNC
Gene Summary: Enables several functions, including 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity; NADPH binding activity; and NADPH dehydrogenase (quinone) activity. Involved in fatty acid biosynthetic process; glycoside metabolic process; and protein tetramerization. Located in mitochondrial matrix. Part of oxidoreductase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01514 | CBR4 Knockout cell line (HeLa) | Human | CBR4 | 1:3~1:6 | Negative | Online Inquiry |
KO01515 | CBR4 Knockout cell line (HCT 116) | Human | CBR4 | 1:2~1:4 | Negative | Online Inquiry |
KO01516 | CBR4 Knockout cell line (HEK293) | Human | CBR4 | 1:3~1:6 | Negative | Online Inquiry |
KO01517 | CBR4 Knockout cell line (A549) | Human | CBR4 | 1:3~1:4 | Negative | Online Inquiry |
CBR4 Gene Knockout Cell Lines represent a key advancement in the study of cellular mechanisms and gene function, derived from the precise editing of the CBR4 gene using cutting-edge CRISPR/Cas9 technology. These genetically modified cell lines are invaluable tools for researchers investigating the role of CBR4, a gene implicated in various metabolic pathways and disease processes, particularly in cancer metabolism and drug resistance. By knocking out this specific gene, researchers can elucidate its physiological function and the biological consequences of its absence, enabling studies that contribute to the understanding of disease etiology and progression.
The primary mechanism through which CBR4 Gene Knockout Cell Lines operate involves the targeted disruption of the CBR4 gene, leading to complete gene inactivation within the cell lines. This allows scientists to observe the downstream effects on cellular pathways and gene expression profiles, offering insights into compensatory mechanisms or alternative pathways that may become activated in the absence of CBR4. Such investigations are critical for the development of novel therapeutic strategies and biomarker identification.
In clinical and research settings, the utility of CBR4 Gene Knockout Cell Lines is further underscored by their ability to serve as standardized models, facilitating reproducible studies that advance our understanding of targeted therapies. Traditional models do not offer the same level of specificity and reliability when it comes to gene function studies, making CBR4 knockout lines a superior alternative for researchers seeking high-quality data.
The key advantages of these cell lines include the precision of gene editing, the robustness of the cell lines in varied culture conditions, and their compatibility with high-throughput screening assays. This combination makes these cell lines indispensable for a wide range of applications in pharmacology, toxicology, and genetics research.
For researchers and clinicians invested in the latest advancements in gene function research, CBR4 Gene Knockout Cell Lines provide a unique opportunity to explore critical biological processes with precision and clarity. Our company brings an extensive background in genetic engineering and cell line development, ensuring you receive products that are not only scientifically rigorous but also tailored to meet the pressing demands of modern biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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