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CBLL1 Knockout Cell Lines

Gene: CBLL1

Official Full Name: Cbl proto-oncogene like 1provided by HGNC

Gene Summary: This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant. [provided by RefSeq, Aug 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20940 CBLL1 Knockout cell line (HeLa) Human CBLL1 1:3~1:6 Negative Online Inquiry
KO20941 CBLL1 Knockout cell line (HCT 116) Human CBLL1 1:2~1:4 Negative Online Inquiry
KO20942 CBLL1 Knockout cell line (HEK293) Human CBLL1 1:3~1:6 Negative Online Inquiry
KO20943 CBLL1 Knockout cell line (A549) Human CBLL1 1:3~1:4 Negative Online Inquiry

Background

CBLL1 Gene Knockout Cell Lines are precisely engineered cellular models designed to facilitate the study of the CBLL1 gene and its functional implications in various biological processes. Utilizing targeted genetic editing technologies, such as CRISPR/Cas9, these cell lines allow for the specific deletion of the CBLL1 gene, enabling researchers to analyze the subsequent phenotypic changes and molecular pathways disrupted by its absence.

The key function of CBLL1 Gene Knockout Cell Lines lies in their ability to elucidate the role of the CBLL1 protein in cellular dynamics, signaling pathways, and potential interactions with other molecular players. By providing a controlled environment to investigate the gene's contribution to processes such as cell proliferation, differentiation, and apoptosis, these knockout models serve as invaluable tools for dissecting complex biological networks. Moreover, the cell lines can be utilized in drug discovery and development, particularly in understanding how CBLL1 influences therapeutic targets or contributes to diseases.

The scientific importance of these knockout cell lines extends to a myriad of applications in both research laboratories and clinical settings, where they can aid in unraveling the underlying mechanisms of various pathological conditions, including cancer and metabolic disorders. Researchers can leverage the unique insights gained from studying the CBLL1 knockout cells to develop innovative therapeutic strategies or biomarkers.

An added advantage of CBLL1 Gene Knockout Cell Lines is that they have undergone rigorous validation, ensuring high specificity and reproducibility in experimental outcomes. Unlike traditional methods that may rely on transient transfection or overexpression systems—often leading to inconsistent results—these stable knockout cell lines provide a more reliable foundation for long-term studies.

For researchers and clinicians keen on advancing their understanding of CBLL1's role in health and disease, these knockout cell lines represent an essential resource. Their capacity to generate robust, replicable data and facilitate translational research underscores their value in the life sciences field.

At [Your Company Name], we pride ourselves on our commitment to innovation and excellence in biological products. Our CBLL1 Gene Knockout Cell Lines embody our expertise in genetic engineering, supporting the research community with high-quality tools that advance scientific discovery and therapeutic development.

Please note that all services are for research use only. Not intended for any clinical use.

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