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CASP2 Knockout Cell Lines

Gene: CASP2

Official Full Name: caspase 2provided by HGNC

Gene Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00012 CASP2 Knockout cell line (Hep G2) Human CASP2 1:2~1:4 Negative Online Inquiry
KO38686 CASP2 Knockout cell line (HeLa) Human CASP2 1:3~1:6 Negative Online Inquiry
KO38687 CASP2 Knockout cell line (HCT 116) Human CASP2 1:2~1:4 Negative Online Inquiry
KO38688 CASP2 Knockout cell line (HEK293) Human CASP2 1:3~1:6 Negative Online Inquiry
KO38689 CASP2 Knockout cell line (A549) Human CASP2 1:3~1:4 Negative Online Inquiry

Background

CASP2 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the functionality and implications of the CASP2 gene, which plays a crucial role in apoptosis and inflammatory responses. These knockout cell lines serve as an invaluable resource for researchers investigating the molecular mechanisms underlying programmed cell death, cellular stress responses, and their implications in various diseases, including cancer and neurodegenerative disorders.

The primary function of CASP2 Gene Knockout Cell Lines is to facilitate the detailed study of the role CASP2 plays in apoptotic signaling pathways. By disrupting the CASP2 gene, these cell lines allow for the observation of downstream effects on cell viability, proliferation, and response to therapeutic agents. Researchers can utilize these knockout models to elucidate the mechanisms by which CASP2 influences other signaling pathways, particularly in the context of apoptosis and inflammation.

From a scientific perspective, the CASP2 Gene Knockout Cell Lines are essential tools in understanding the complexities of cellular life and death, paving the way for innovations in drug development and therapeutic interventions. Their applications extend into both basic research and clinical settings, offering insights that could lead to novel treatments for conditions such as cancer, where dysregulation of apoptosis is a hallmark.

What sets these cell lines apart from traditional models is their specificity and precision in targeting the CASP2 gene, ensuring reliable and reproducible results in experiments. Furthermore, these knockout models can save researchers valuable time and resources by providing clear evidence of the gene's role in various cellular processes without the confounding variables present in wild-type cells.

For researchers and clinicians looking to deepen their understanding of apoptotic pathways or to explore new therapeutic possibilities, CASP2 Gene Knockout Cell Lines represent a vital asset. They are engineered with the highest quality standards, ensuring consistent performance and reliability in experimental applications.

Our company specializes in the development and provision of advanced biological products, driven by cutting-edge research and a commitment to excellence. With a focus on delivering precisely engineered models, we empower scientists to achieve breakthrough discoveries in the field of molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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