Gene: CARMIL1
Official Full Name: capping protein regulator and myosin 1 linker 1provided by HGNC
Gene Summary: Involved in several processes, including actin filament network formation; plasma membrane bounded cell projection organization; and positive regulation of cellular component organization. Located in several cellular components, including lamellipodium; macropinosome; and nuclear speck. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19081 | CARMIL1 Knockout cell line (HeLa) | Human | CARMIL1 | 1:3~1:6 | Negative | Online Inquiry |
KO19082 | CARMIL1 Knockout cell line (HCT 116) | Human | CARMIL1 | 1:2~1:4 | Negative | Online Inquiry |
KO19083 | CARMIL1 Knockout cell line (HEK293) | Human | CARMIL1 | 1:3~1:6 | Negative | Online Inquiry |
KO19084 | CARMIL1 Knockout cell line (A549) | Human | CARMIL1 | 1:3~1:4 | Negative | Online Inquiry |
CARMIL1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the CARMIL1 gene, a critical component linked to cytoskeletal dynamics and cellular signaling pathways. These knockout cell lines enable researchers to study the specific functions and regulatory mechanisms of CARMIL1 in various biological contexts. With precise gene editing technology, such as CRISPR/Cas9, these cell lines provide a robust platform for investigating the role of CARMIL1 in cell adhesion, migration, and immune responses, thereby elucidating its contribution to processes such as cancer progression and autoimmune diseases.
The primary mechanism of action of CARMIL1 involves regulating actin filament dynamics and coordinating with other signaling proteins to facilitate cellular movement and morphology changes. By disrupting this gene, researchers can observe phenotypic changes, analyze alterations in signaling pathways, and assess the impact on cellular behavior, offering valuable insights into disease mechanisms.
In a research or clinical setting, CARMIL1 Gene Knockout Cell Lines hold significant scientific importance. They serve as essential tools for drug discovery, where the understanding of CARMIL1's role can lead to novel therapeutic approaches. Furthermore, these cell lines are advantageous in comparative studies to evaluate the effects of potential treatments across different genetic backgrounds, enhancing the precision of experimental results.
Compared to conventional cell lines, the unique selling points of CARMIL1 Gene Knockout Cell Lines include their specificity in targeting CARMIL1 and the ability to provide consistent and reproducible data on gene function and interaction in various experimental designs. This specificity aids researchers in drawing clearer conclusions about the mechanistic role of CARMIL1 compared to standard models.
By investing in CARMIL1 Gene Knockout Cell Lines, researchers and clinicians gain access to invaluable tools that can accelerate their studies and drive forward innovative findings in cellular biology. Our company brings expertise in gene editing and cell culture technologies, ensuring that our products meet the highest standards for scientific research and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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