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CAMTA1 Knockout Cell Lines

Gene: CAMTA1

Official Full Name: calmodulin binding transcription activator 1provided by HGNC

Gene Summary: The protein encoded by this gene contains a CG1 DNA-binding domain, a transcription factor immunoglobulin domain, ankyrin repeats, and calmodulin-binding IQ motifs. The encoded protein is thought to be a transcription factor and may be a tumor suppressor. However, a translocation event is sometimes observed between this gene and the WWTR1 gene, with the resulting WWTR1-CAMTA1 oncoprotein leading to epithelioid hemangioendothelioma, a malignant vascular cancer. [provided by RefSeq, Mar 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06564 CAMTA1 Knockout cell line (HeLa) Human CAMTA1 1:3~1:6 Negative Online Inquiry
KO06565 CAMTA1 Knockout cell line (HCT 116) Human CAMTA1 1:2~1:4 Negative Online Inquiry
KO06566 CAMTA1 Knockout cell line (HEK293) Human CAMTA1 1:3~1:6 Negative Online Inquiry
KO06567 CAMTA1 Knockout cell line (A549) Human CAMTA1 1:3~1:4 Negative Online Inquiry

Background

CAMTA1 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate the study of the CAMTA1 gene, which plays a crucial role in various physiological processes and human diseases. These knockout cell lines are generated using advanced CRISPR/Cas9 gene-editing technology, wherein the CAMTA1 gene has been selectively disrupted, allowing researchers to investigate its functions and interactions in a controlled environment.

The primary mechanism of action involves the deletion or modification of the CAMTA1 gene, leading to a loss of its protein product, which is implicated in transcriptional regulation and cellular signaling pathways. By utilizing these knockout lines, scientists can assess the downstream effects on cellular processes such as differentiation, proliferation, and stress response. This provides a powerful platform to elucidate the role of CAMTA1 in disease mechanisms, including cancer and neurodegenerative disorders.

The scientific significance of CAMTA1 Gene Knockout Cell Lines is underscored by their applicability in both basic and translational research settings. Researchers can leverage these models to explore the functional consequences of CAMTA1 deficiency and its potential as a biomarker or therapeutic target. Additionally, these knockout cell lines hold promise for drug discovery efforts, allowing pharmaceutical companies to screen compounds that may modulate the activity of pathways involving CAMTA1.

What sets our CAMTA1 Gene Knockout Cell Lines apart from alternative products is their high reliability and reproducibility. Each cell line undergoes extensive validation to confirm the efficiency of gene knockout and the consistency of phenotypic expression, ensuring that researchers receive robust models suited for their experimental needs. Furthermore, our cell lines are available in various genetic backgrounds, providing versatile options for specific research applications.

For researchers and clinicians alike, the CAMTA1 Gene Knockout Cell Lines represent an invaluable tool that catalyzes breakthroughs in understanding gene function and disease pathology. By integrating these knockout lines into their studies, users can generate more reliable and reproducible data, ultimately leading to impactful scientific discoveries.

Our company prides itself on its expertise in developing high-quality biological research products, driven by a commitment to innovation and excellence. With a focus on genetic engineering and cellular model systems, we are dedicated to equipping researchers with the tools necessary to advance their studies and contribute to the field of biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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