Gene: C2orf49
Official Full Name: chromosome 2 open reading frame 49provided by HGNC
Gene Summary: Predicted to be involved in tRNA splicing, via endonucleolytic cleavage and ligation. Located in nucleoplasm. Part of tRNA-splicing ligase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19298 | C2orf49 Knockout cell line (HeLa) | Human | C2orf49 | 1:3~1:6 | Negative | Online Inquiry |
KO19299 | C2orf49 Knockout cell line (HCT 116) | Human | C2orf49 | 1:2~1:4 | Negative | Online Inquiry |
KO19300 | C2orf49 Knockout cell line (HEK293) | Human | C2orf49 | 1:3~1:6 | Negative | Online Inquiry |
KO19301 | C2orf49 Knockout cell line (A549) | Human | C2orf49 | 1:3~1:4 | Negative | Online Inquiry |
C2orf49 Gene Knockout Cell Lines are genetically modified cell lines in which the C2orf49 gene has been rendered nonfunctional through a knockout approach. The process of creating these knockout lines typically involves CRISPR-Cas9 technology or similar gene-editing techniques, allowing for precise alterations at the genomic level. This product enables researchers to investigate the role of the C2orf49 gene in various cellular processes, particularly in the context of diseases such as cancer, neurological disorders, and metabolic syndromes. By observing the phenotypic changes accompanying the loss of C2orf49 function, scientists can elucidate its biological significance and contribute to a clearer understanding of gene function and regulation.
The primary mechanism underlying the utility of C2orf49 knockout cell lines is the ability to create a defined genetic model that mimics human conditions in vitro. This facilitates research into the gene's contributions to pathways such as cell proliferation, apoptosis, and transcription regulation. The availability of these knockout lines opens avenues for drug development, biomarker discovery, and functional studies that require precise genetic backgrounds.
Compared to alternative approaches, such as transient transfection or RNA interference, gene knockout offers lasting and stable gene disruption, providing more reliable data and enhancing reproducibility in experimental outcomes. Furthermore, these cell lines can serve as invaluable tools for high-throughput screening assays and validation studies, thereby accelerating research timelines.
For researchers and clinicians, the C2orf49 Gene Knockout Cell Lines represent a valuable asset in the quest to understand gene function and its implications in health and disease. The ability to dissect genetic roles in cellular contexts aids in identifying potential therapeutic targets and biomarkers for clinical applications.
Our company specializes in innovative biological products, delivering high-quality cell lines with extensive documentation and technical support. We are committed to empowering the scientific community with tools that drive discovery and translation in biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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