Home / C2CD3 Knockout Cell Lines

C2CD3 Knockout Cell Lines

Gene: C2CD3

Official Full Name: C2 domain containing 3 centriole elongation regulatorprovided by HGNC

Gene Summary: This gene encodes a protein that functions as a regulator of centriole elongation. Studies of the orthologous mouse protein show that it promotes centriolar distal appendage assembly and is also required for the recruitment of other ciliogenic proteins, including intraflagellar transport proteins. Mutations in this gene cause orofaciodigital syndrome XIV (OFD14), a ciliopathy resulting in malformations of the oral cavity, face and digits. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28491 C2CD3 Knockout cell line (HeLa) Human C2CD3 1:3~1:6 Negative Online Inquiry
KO28492 C2CD3 Knockout cell line (HCT 116) Human C2CD3 1:2~1:4 Negative Online Inquiry
KO28493 C2CD3 Knockout cell line (HEK293) Human C2CD3 1:3~1:6 Negative Online Inquiry
KO28494 C2CD3 Knockout cell line (A549) Human C2CD3 1:3~1:4 Negative Online Inquiry

Background

C2CD3 Gene Knockout Cell Lines are precisely engineered cellular models designed to facilitate the study of C2CD3 gene function and its associated pathways. These cell lines have been created through advanced CRISPR/Cas9 genetic editing techniques, allowing for the specific deletion of the C2CD3 gene. This targeted approach provides researchers with a powerful tool to investigate the biological roles of C2CD3 in various cellular processes, including ciliary assembly, intracellular transport, and signal transduction.

The primary function of the C2CD3 Gene Knockout Cell Lines lies in their ability to mimic a loss-of-function scenario, thereby enabling the exploration of the consequences of C2CD3 deficiency. By examining these effects, researchers can elucidate the gene's involvement in diseases linked to ciliary dysfunction, such as ciliopathies, and provide insights into potential therapeutic targets. The knockout mechanism not only allows for the study of abnormal cellular behaviors but also aids in the validation of hypotheses related to the gene’s contributions to fundamental biological pathways.

In the context of research and clinical settings, these cell lines play a crucial role in understanding the genetic underpinnings of disease states. Their utility spans a wide range of applications, from basic biological studies to drug discovery and development, offering the potential to uncover new interventions for ciliary-related disorders. Compared to alternative methods such as RNA interference, the knockout cell lines provide a more permanent and precise alteration of gene function, leading to robust and replicable experimental outcomes.

The value of C2CD3 Gene Knockout Cell Lines extends beyond basic research, making them an essential asset for researchers and clinicians aiming to address pressing questions in genetics, molecular biology, and medicine. They empower users to investigate gene functions in native contexts, ultimately driving forward our understanding of complex biological systems and paving the way for innovative therapeutic solutions.

Our company specializes in providing high-quality biological tools and reagents, and C2CD3 Gene Knockout Cell Lines exemplify our commitment to advancing research through innovative and reliable products. With a strong focus on customer support and scientific accuracy, we are dedicated to helping the scientific community accelerate discoveries that can lead to transformative healthcare solutions.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.