Gene: C1S
Official Full Name: complement C1sprovided by HGNC
Gene Summary: This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38761 | C1S Knockout cell line (HeLa) | Human | C1S | 1:3~1:6 | Negative | Online Inquiry |
KO38762 | C1S Knockout cell line (HCT 116) | Human | C1S | 1:2~1:4 | Negative | Online Inquiry |
KO38763 | C1S Knockout cell line (HEK293) | Human | C1S | 1:3~1:6 | Negative | Online Inquiry |
KO38764 | C1S Knockout cell line (A549) | Human | C1S | 1:3~1:4 | Negative | Online Inquiry |
C1S Gene Knockout Cell Lines are specialized cellular models designed to study the biological functions and implications of the complement component C1s gene in various physiological and pathological contexts. These cell lines undergo a CRISPR-Cas9 mediated gene knockout, which effectively disrupts the expression of the C1S gene, allowing researchers to examine the resulting phenotypic changes and underlying molecular mechanisms.
The primary function of C1S in the body is its role in the complement system, specifically in mediating immune responses and inflammatory processes. By utilizing C1S Gene Knockout Cell Lines, scientists can elucidate the effects of C1s deficiency, which may lead to insights into complement-related diseases, immune dysregulation, and potential therapeutic interventions. Understanding the role of C1s provides pivotal information not only for immunological research but also for developing targeted therapies in conditions like autoimmune diseases, sepsis, and other inflammation-mediated disorders.
Compared to alternative models, the C1S Gene Knockout Cell Lines offer distinct advantages, including precise gene editing, reproducibility, and a minimal background effect, which enhance experimental clarity. This specificity allows researchers to confidently attribute observed changes to C1S disruption. Furthermore, the use of these cell lines may accelerate drug discovery processes and the development of gene therapies, making them invaluable tools in both academic and industrial research.
For researchers and clinicians, the ability to manipulate and analyze the function of the C1s gene opens pathways for new therapeutic strategies and enhances understanding of immune system intricacies. By providing robust and reliable cell lines, we empower our users to push the boundaries of current biological research. Our company prides itself on delivering high-quality biological products backed by extensive expertise in gene editing technologies and cellular biology, ensuring that users have the best tools at their disposal for transformative scientific exploration.
Please note that all services are for research use only. Not intended for any clinical use.
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