Gene: C1R
Official Full Name: complement C1rprovided by HGNC
Gene Summary: This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome. [provided by RefSeq, Dec 2018]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO07145 | C1R Knockout cell line (HeLa) | Human | C1R | 1:3~1:6 | Negative | Online Inquiry |
KO07146 | C1R Knockout cell line (HCT 116) | Human | C1R | 1:2~1:4 | Negative | Online Inquiry |
KO07147 | C1R Knockout cell line (HEK293) | Human | C1R | 1:3~1:6 | Negative | Online Inquiry |
KO07148 | C1R Knockout cell line (A549) | Human | C1R | 1:3~1:4 | Negative | Online Inquiry |
C1R Gene Knockout Cell Lines are specialized biological tools designed for advanced research applications. These cell lines consist of genetically modified C1R cells in which specific genes have been knocked out using CRISPR-Cas9 technology. This process allows researchers to investigate the functions of particular genes by observing resultant phenotypic changes, thus enabling a deeper understanding of cellular processes, disease mechanisms, and therapeutic targets.
The primary mechanism of action involves the targeted disruption of gene sequences, leading to the loss of gene expression. This allows scientists to assess the role of specific genes in various biological pathways, immune responses, or cellular signaling mechanisms. By utilizing these knockout cell lines, researchers can create more accurate models of human diseases, evaluate drug efficacy, and investigate gene functions in immune response or cancer biology.
The scientific importance of C1R Gene Knockout Cell Lines cannot be understated, as they are integral for both basic and applied research. In clinical settings, these cell lines serve as critical tools for drug discovery, providing insights into therapeutic avenues and potential side effects. Their robustness and versatility make them particularly valuable for studying interactions in the immune system and developing vaccine strategies or cancer therapies.
Compared to traditional cell lines, C1R Gene Knockout Cell Lines offer distinct advantages, including higher specificity in gene modification, better reproducibility, and the potential for multipurpose applications across various research areas. Their ease of use and the capability to generate specific phenotypes without confounding effects positions them as superior alternatives in gene function studies.
For researchers and clinicians focused on exploring genetic pathways or developing new therapeutics, C1R Gene Knockout Cell Lines represent an indispensable resource that can significantly accelerate scientific discovery. Our company specializes in providing reliable and high-quality biological products, ensuring our customers have access to advanced research tools that meet their evolving needs.
Please note that all services are for research use only. Not intended for any clinical use.
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