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C11orf80 Knockout Cell Lines

Gene: C11orf80

Official Full Name: TOP6B like initiator of meiotic double strand breaksprovided by HGNC

Gene Summary: Predicted to be involved in meiotic DNA double-strand break formation and reciprocal meiotic recombination. Predicted to be located in chromosome. Implicated in gestational trophoblastic neoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19200 C11orf80 Knockout cell line (HeLa) Human C11orf80 1:3~1:6 Negative Online Inquiry
KO19201 C11orf80 Knockout cell line (HCT 116) Human C11orf80 1:2~1:4 Negative Online Inquiry
KO19202 C11orf80 Knockout cell line (HEK293) Human C11orf80 1:3~1:6 Negative Online Inquiry
KO19203 C11orf80 Knockout cell line (A549) Human C11orf80 1:3~1:4 Negative Online Inquiry

Background

C11orf80 Gene Knockout Cell Lines represent a significant advancement in the toolkit available for genetic research, particularly in the study of gene function and disease mechanisms. These specialized cell lines are engineered to lack the C11orf80 gene, allowing researchers to investigate the biological consequences of its absence. By utilizing CRISPR/Cas9 technology, these cell lines provide a precise and effective approach to knockout studies, facilitating a deep understanding of the gene's role in various cellular processes.

The primary function of the C11orf80 gene knockout cell lines lies in their ability to elucidate the biological pathways in which C11orf80 is involved. Researchers can employ these cell lines to observe changes in cellular behavior, signal transduction, and gene expression profiles that result from the gene’s silencing. This makes them invaluable for studies on cellular responses to stress, metabolic changes, and potential links to various pathologies, including cancer, where gene expression regulation is crucial.

The scientific importance of these cell lines extends into both basic and applied research settings. In basic research, scientists can contribute to the understanding of gene functions and the underlying mechanisms of genetic disorders. Clinically, these lines provide a platform for drug discovery, enabling screening for therapeutic targets that may interact with the C11orf80 gene, thus sparking innovations in personalized medicine approaches.

One of the primary advantages of the C11orf80 Gene Knockout Cell Lines is their specificity and reliability in experimental outcomes. Unlike other gene editing methods, CRISPR technology offers higher precision, goal-directed editing with less off-target effects, thus enhancing the validity of research findings. These cell lines also fulfill a crucial demand for standardized biological models, improving reproducibility and comparability across studies.

For researchers and clinicians dedicated to advancing genetic research, the C11orf80 gene knockout cell lines serve as an essential resource. They complement a comprehensive biological research portfolio that could illuminate novel therapeutic pathways and improve clinical results. Our company, with extensive expertise in genetic engineering and a commitment to quality, offers these vital tools to empower the scientific community in addressing complex biological questions and major health challenges.

Please note that all services are for research use only. Not intended for any clinical use.

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