Gene: C11orf65
Official Full Name: chromosome 11 open reading frame 65provided by HGNC
Gene Summary: Predicted to be involved in negative regulation of mitochondrial fission and negative regulation of protein targeting to mitochondrion. Predicted to be located in cytosol and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20371 | C11orf65 Knockout cell line (HCT 116) | Human | C11orf65 | 1:2~1:4 | Negative | Online Inquiry |
C11orf65 Gene Knockout Cell Lines are genetically engineered cell lines that have had the C11orf65 gene functionally disrupted, enabling researchers to study the biological effects and pathways associated with this specific gene. This product utilizes state-of-the-art CRISPR-Cas9 technology for precise gene editing, allowing for the removal of C11orf65, a gene implicated in various cellular processes and pathways, including those related to neurodegeneration and mitochondrial function.
The key mechanism of action involves the targeting of the C11orf65 gene locus, where the CRISPR machinery induces double-strand breaks, subsequently leading to errors during repair that effectively knock out the gene. This creates an ideal model for investigating the phenotypic consequences of C11orf65 loss, thus providing insights into its role in health and disease.
The scientific importance of C11orf65 Gene Knockout Cell Lines lies in their utility for research into neurological disorders and mitochondrial diseases, where understanding the role of specific genes can inform therapeutic strategies. Clinically, these cell lines facilitate the exploration of potential drug targets, disease mechanisms, and the development of gene therapies.
Compared to conventional knockout methodologies, our C11orf65 Gene Knockout Cell Lines offer superior specificity and efficiency, minimizing off-target effects and ensuring reliable data generation. Additionally, these cell lines come well-characterized and validated, enabling researchers to swiftly integrate them into their experimental workflows.
For researchers and clinicians alike, the C11orf65 Gene Knockout Cell Lines represent a valuable tool for elucidating gene function and pathology, ultimately yielding advancements in understanding disease states and therapeutic innovation. Our company prides itself on its expertise in cutting-edge genetic technologies, providing high-quality biological products that empower scientific discovery and application.
Please note that all services are for research use only. Not intended for any clinical use.
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