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BTBD1 Knockout Cell Lines

Gene: BTBD1

Official Full Name: BTB domain containing 1provided by HGNC

Gene Summary: The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21977 BTBD1 Knockout cell line (HeLa) Human BTBD1 1:3~1:6 Negative Online Inquiry
KO21978 BTBD1 Knockout cell line (HCT 116) Human BTBD1 1:2~1:4 Negative Online Inquiry
KO21979 BTBD1 Knockout cell line (HEK293) Human BTBD1 1:3~1:6 Negative Online Inquiry
KO21980 BTBD1 Knockout cell line (A549) Human BTBD1 1:3~1:4 Negative Online Inquiry

Background

BTBD1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the BTBD1 gene, enabling researchers to study the gene's function and associated pathways in depth. BTBD1 is implicated in various cellular processes including signal transduction, protein degradation, and transcriptional regulation, making these knockout lines essential tools for unraveling its role in health and disease.

The primary mechanism by which these knockout cell lines operate is through the targeted deletion of the BTBD1 gene using advanced CRISPR-Cas9 technology. This precise editing creates a cellular environment that allows for the observation of phenotypic changes in the absence of BTBD1 expression. Researchers can utilize these cell lines to investigate the implications of BTBD1-related mutations or deficiencies, contributing valuable insights into the gene's potential links to cancer, neurodegenerative disorders, and metabolic syndromes.

The scientific importance of BTBD1 Gene Knockout Cell Lines extends into various research and clinical applications, including drug discovery, biomarker identification, and mechanistic studies of diseases. Their use can accelerate understanding of complex biological systems and facilitate the development of targeted therapies. Furthermore, these cell lines serve as indispensable models for validating hypotheses related to gene function and protein interactions.

One of the key advantages of using our BTBD1 Gene Knockout Cell Lines is the unparalleled specificity and reproducibility that comes from utilizing state-of-the-art gene editing techniques. Compared to traditional knockdown models, which may yield incomplete suppression of gene expression, these knockout lines provide a more definitive means to explore the biological implications of BTBD1 absence. Additionally, they come with comprehensive documentation of performance metrics and validation studies to ensure reliability and ease of use in the lab.

For researchers and clinicians focused on genetic research, discovering novel therapeutics, or elucidating disease pathology, the BTBD1 Gene Knockout Cell Lines represent a vital resource that can drive impactful innovations. Our company is dedicated to providing high-quality biological products that empower scientific discovery. With a commitment to advancing the field, we continuously strive to enhance our offerings, ensuring that researchers have access to the most relevant and cutting-edge tools available.

Please note that all services are for research use only. Not intended for any clinical use.

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