Gene: BRMS1L
Official Full Name: BRMS1 like transcriptional repressorprovided by HGNC
Gene Summary: The protein encoded by this gene shows sequence similarity to the human breast carcinoma metastasis suppressor (BRMS1) protein and the mammalian Sds3 (suppressor of defective silencing 3) proteins. This protein is a component of the mSin3a family of histone deacetylase complexes (HDAC). [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24944 | BRMS1L Knockout cell line (HeLa) | Human | BRMS1L | 1:3~1:6 | Negative | Online Inquiry |
KO24945 | BRMS1L Knockout cell line (HCT 116) | Human | BRMS1L | 1:2~1:4 | Negative | Online Inquiry |
KO24946 | BRMS1L Knockout cell line (HEK293) | Human | BRMS1L | 1:3~1:6 | Negative | Online Inquiry |
KO24947 | BRMS1L Knockout cell line (A549) | Human | BRMS1L | 1:3~1:4 | Negative | Online Inquiry |
BRMS1L Gene Knockout Cell Lines are specifically engineered mammalian cell lines that have undergone targeted gene disruption to eliminate the expression of the BRMS1L gene. This cell line model is invaluable for researchers interested in studying the role of BRMS1L in various biological processes, including tumor progression, immune response regulation, and cellular signaling pathways. The knockout of BRMS1L allows for in-depth investigation into its function and interaction within cellular networks, providing insights into its contributions to pathophysiological conditions.
The mechanism behind these knockout cell lines involves advanced gene editing technologies, such as CRISPR-Cas9, which enable precise and efficient modification of the genomic DNA. By removing the BRMS1L gene, researchers can assess the phenotype changes, gene expression profiles, and metabolic functions that arise from this disruption, paving the way for enhanced understanding of its biological significance and potential therapeutic implications.
Scientifically, BRMS1L plays a key role in cancer biology, where its loss may correlate with increased metastatic potential. Therefore, these cell lines are essential tools in various research applications, including drug discovery, the evaluation of gene function, and elucidation of gene regulatory mechanisms in both cancer and non-cancer conditions.
When compared to alternative models, BRMS1L Gene Knockout Cell Lines offer specific advantages, such as stable genetic modification, reproducibility across experiments, and the ability to easily evaluate the downstream effects of gene loss in controlled environments. These attributes streamline the research process, reducing variables and thereby enhancing the reliability of experimental outcomes.
For researchers and clinicians, the availability of these knockout cell lines represents an opportunity to unlock new pathways in biomedical research and develop targeted therapies. The ability to manipulate specific genes efficiently accelerates the pace of discovery in understanding complex diseases.
Our company prides itself on its expertise in genetic engineering and cell line development, consistently delivering high-quality biological research tools that empower scientists to advance their research goals. With our BRMS1L Gene Knockout Cell Lines, we are committed to providing innovative solutions that facilitate significant discoveries in molecular and cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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