Gene: BEND6
Official Full Name: BEN domain containing 6provided by HGNC
Gene Summary: Enables transcription corepressor activity. Predicted to be involved in negative regulation of Notch signaling pathway and positive regulation of neuron differentiation. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27512 | BEND6 Knockout cell line (HeLa) | Human | BEND6 | 1:3~1:6 | Negative | Online Inquiry |
KO27513 | BEND6 Knockout cell line (HCT 116) | Human | BEND6 | 1:2~1:4 | Negative | Online Inquiry |
KO27514 | BEND6 Knockout cell line (HEK293) | Human | BEND6 | 1:3~1:6 | Negative | Online Inquiry |
KO27515 | BEND6 Knockout cell line (A549) | Human | BEND6 | 1:3~1:4 | Negative | Online Inquiry |
BEND6 Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the study of the biological functions of the BEND6 gene, a crucial player in a variety of cellular processes. These cell lines are created using advanced CRISPR/Cas9 gene-editing technology, which allows for precise knockout of the BEND6 gene, resulting in a cellular environment that exhibits the loss of BEND6 expression. This model system is pivotal for dissecting the role of BEND6 in cell signaling, differentiation, and disease pathology, offering insights that are otherwise elusive in wild-type models.
The primary mechanisms underlying these knockout cell lines include targeted gene disruption, allowing researchers to analyze phenotypic changes associated with loss of BEND6 function. By utilizing these cell lines, scientists can conduct high-throughput screens to identify pathways affected by BEND6 deletion, thus unraveling its role in complex diseases such as cancer and developmental disorders. Such research is essential for developing targeted therapies and understanding disease mechanisms at a molecular level.
What sets BEND6 Gene Knockout Cell Lines apart from traditional models is their specificity and reliability. While conventional models often display compensatory mechanisms that mask the effects of gene deletion, our cell lines exhibit a clear phenotype attributable to the BEND6 knockout. This specificity not only enhances experimental reproducibility but also streamlines the process of discovery, giving researchers a significant advantage in their investigations.
For researchers and clinicians focused on molecular biology, genetics, and therapeutic development, BEND6 Gene Knockout Cell Lines represent an invaluable tool. Their application in preclinical studies can accelerate the path toward understanding and treating diseases linked to BEND6 dysfunction. Choosing our product reflects a commitment to high-quality, cutting-edge research tools essential for groundbreaking discoveries.
Our company is dedicated to advancing scientific knowledge through the development of innovative biological products, ensuring that researchers have access to quality resources that align with the most current advancements in molecular biology techniques.
Please note that all services are for research use only. Not intended for any clinical use.
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