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BCL2L13 Knockout Cell Lines

Gene: BCL2L13

Official Full Name: BCL2 like 13provided by HGNC

Gene Summary: This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06742 BCL2L13 Knockout cell line (HeLa) Human BCL2L13 1:3~1:6 Negative Online Inquiry
KO06743 BCL2L13 Knockout cell line (HCT 116) Human BCL2L13 1:2~1:4 Negative Online Inquiry
KO06744 BCL2L13 Knockout cell line (HEK293) Human BCL2L13 1:3~1:6 Negative Online Inquiry
KO06745 BCL2L13 Knockout cell line (A549) Human BCL2L13 1:3~1:4 Negative Online Inquiry

Background

BCL2L13 Gene Knockout Cell Lines are specialized cellular models designed to facilitate research into the biological functions of the BCL2L13 gene, which encodes a member of the B-cell lymphoma 2 (Bcl-2) protein family. These knockout cell lines enable scientists to investigate the role of BCL2L13 in cellular processes such as apoptosis, stress response, and oncogenesis by providing a platform where the gene has been intentionally inactivated.

The key functionality of these cell lines lies in their ability to precisely model the loss-of-function effects associated with BCL2L13. By examining the resultant phenotypic changes, researchers can elucidate the mechanisms through which BCL2L13 influences cellular health and survival pathways. This insight is pivotal, as alterations in BCL2L13 expression levels have been linked to various diseases, including cancer.

In terms of scientific importance, BCL2L13 Gene Knockout Cell Lines serve as invaluable tools in research settings focused on apoptosis, cancer biology, and drug resistance studies. They enable high-throughput screening for therapeutic agents aimed at modulating cell death pathways, offering a direct application for clinicians looking to develop novel cancer treatments.

The specific advantages of using these knockout cell lines over alternatives include their robustness in delivering consistent and reproducible results, which is crucial for advancing the understanding of complex gene interactions. Unlike traditional methods of gene knockdown, which can yield variable outcomes, knockout cell lines provide a clean genetic background devoid of BCL2L13, thereby ensuring clarity in experimental results.

For researchers, clinicians, and pharmaceutical developers, the BCL2L13 Gene Knockout Cell Lines present a powerful resource that opens avenues for targeted discovery and therapeutic innovation. These cell lines are engineered under stringent quality controls to ensure reliability in experimental setups. Our company brings extensive expertise in cellular model development, providing researchers access to high-quality biological products tailored to meet the rigorous demands of modern scientific inquiry.

Please note that all services are for research use only. Not intended for any clinical use.

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