Gene: BCDIN3D
Official Full Name: BCDIN3 domain containing RNA methyltransferaseprovided by HGNC
Gene Summary: This gene encodes an RNA methyltransferase which belongs to the rossmann fold methyltransferase family, and serves as a 5'-methylphosphate capping enzyme that is specific for cytoplasmic histidyl tRNA. The encoded protein contains an S-adenosylmethionine binding domain and uses the methyl group donor, S-adenosylmethionine. This gene is overexpressed in breast cancer cells, and is related to the tumorigenic phenotype and poor prognosis of breast cancer. The encoded protein is thought to promote the cellular invasion of breast cancer cells, by downregulating the expression of tumor suppressor miRNAs through the dimethylation of the 5-monophosphate of the corresponding precursor miRNAs. [provided by RefSeq, Apr 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24124 | BCDIN3D Knockout cell line (HeLa) | Human | BCDIN3D | 1:3~1:6 | Negative | Online Inquiry |
KO24125 | BCDIN3D Knockout cell line (HCT 116) | Human | BCDIN3D | 1:2~1:4 | Negative | Online Inquiry |
KO24126 | BCDIN3D Knockout cell line (HEK293) | Human | BCDIN3D | 1:3~1:6 | Negative | Online Inquiry |
KO24127 | BCDIN3D Knockout cell line (A549) | Human | BCDIN3D | 1:3~1:4 | Negative | Online Inquiry |
BCDIN3D Gene Knockout Cell Lines are a specialized tool designed for the study of gene function and regulation in mammalian cells. These cell lines are engineered to contain knockout mutations in the BCDIN3D gene, which is implicated in the regulation of several biological pathways, including those involved in cellular stress responses and epigenetic modifications. By employing CRISPR-Cas9 technology or other gene-editing techniques, this product allows researchers to create specific, targeted disruptions in the gene sequence, enabling the investigation of gene function with high precision.
The primary function of BCDIN3D Gene Knockout Cell Lines is to elucidate the biological roles of the BCDIN3D protein through loss-of-function studies. Researchers can assess cellular phenotypes, analyze pathways impacted by the absence of the BCDIN3D protein, and explore its interaction with other molecular players. The ability to create cell lines with specific gene deletions facilitates advanced experimental designs and provides invaluable models for disease research, drug discovery, and therapeutic development in both basic and translational sciences.
Scientifically, BCDIN3D has garnered increased attention for its potential role in cellular aging and cancer biology. Its knockout cell lines are instrumental in studying how BCDIN3D contributes to aberrant cellular behavior and developing strategies to target related pathways in clinical settings. Compared to alternatives such as RNA interference models, BCDIN3D Gene Knockout Cell Lines offer a more stable, permanent alteration that provides reproducibility and clarity in experimental results.
The unique selling points of these knockout cell lines include their high specificity and efficiency, which minimize off-target effects commonly associated with other gene manipulation techniques. Researchers and clinicians will find immense value in these cell lines as they enable the dissection of complex biological systems and contribute to advancing knowledge in genetic research and therapeutic applications.
Our company brings years of expertise in developing high-quality biological tools, ensuring that our BCDIN3D Gene Knockout Cell Lines meet rigorous standards of reliability and performance for the scientific community, empowering researchers to push the boundaries of genetic inquiry.
Please note that all services are for research use only. Not intended for any clinical use.
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