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BBX Knockout Cell Lines

Gene: BBX

Official Full Name: BBX high mobility group box domain containingprovided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within bone development. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20568 BBX Knockout cell line (HeLa) Human BBX 1:3~1:6 Negative Online Inquiry
KO20569 BBX Knockout cell line (HCT 116) Human BBX 1:2~1:4 Negative Online Inquiry
KO20570 BBX Knockout cell line (HEK293) Human BBX 1:3~1:6 Negative Online Inquiry
KO20571 BBX Knockout cell line (A549) Human BBX 1:3~1:4 Negative Online Inquiry

Background

BBX Gene Knockout Cell Lines are a specialized set of genetically modified cell lines designed to facilitate the study of gene function by enabling researchers to create targeted knockouts of the BBX gene, renowned for its role in cellular differentiation and development. These cell lines employ CRISPR-Cas9 technology, which utilizes a programmable RNA-guided endonuclease to create double-strand breaks at specific genomic locations, leading to targeted gene disruption. This precise mechanism ensures that alterations in the BBX gene can be studied effectively, allowing for comprehensive investigations into the gene's contributions to various biological processes.

The scientific importance of BBX Gene Knockout Cell Lines lies in their capacity to provide critical insights into the functions of BBX in both basic and applied research settings. These cell lines are invaluable in elucidating the molecular pathways involving BBX, contributing to advancements in understanding diseases linked to its dysfunction, such as certain cancers and developmental disorders. Moreover, they serve as essential tools in drug discovery and therapeutic research, enabling the evaluation of potential therapies through functional assays and phenotypic analyses.

One of the key advantages of BBX Gene Knockout Cell Lines is their high specificity and efficiency compared to traditional gene knockout methods, such as homologous recombination, which can be time-consuming and less precise. Additionally, these cell lines are validated for consistent performance and reproducibility in various experimental contexts, providing researchers with reliable models for their studies. The ease of use, combined with the wide applicability in diverse experimental settings, establishes BBX Gene Knockout Cell Lines as an essential resource for both academic and industrial laboratories.

For researchers and clinicians focused on genetic studies, the BBX Gene Knockout Cell Lines present a valuable asset that enhances experimental robustness and accelerates discoveries in gene function and regulation. Our commitment to developing high-quality, innovative biological products is bolstered by our expertise in genetic engineering and cell biology, ensuring that our customers have access to cutting-edge tools to advance their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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