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BBIP1 Knockout Cell Lines

Gene: BBIP1

Official Full Name: BBSome interacting protein 1provided by HGNC

Gene Summary: This gene encodes one of eight proteins that form the BBSome complex and is essential for its assembly. The BBSome complex is involved in trafficking signal receptors to and from the cilia. Mutations in this gene result in Bardet-Biedl syndrome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22943 BBIP1 Knockout cell line (HeLa) Human BBIP1 1:3~1:6 Negative Online Inquiry
KO22944 BBIP1 Knockout cell line (HCT 116) Human BBIP1 1:2~1:4 Negative Online Inquiry
KO22945 BBIP1 Knockout cell line (HEK293) Human BBIP1 1:3~1:6 Negative Online Inquiry
KO22946 BBIP1 Knockout cell line (A549) Human BBIP1 1:3~1:4 Negative Online Inquiry

Background

BBIP1 Gene Knockout Cell Lines represent a novel tool for investigating the functional roles of the BBIP1 gene in cellular processes. Created using advanced CRISPR-Cas9 gene editing technology, these knockout cell lines provide researchers with the ability to study the consequences of BBIP1 depletion in various biological contexts. The specific knockout of the BBIP1 gene enables the exploration of pathways associated with cellular stress responses, apoptosis, and metabolic regulation, making it a pivotal resource for understanding tumor biology and potential therapeutic targets in cancer research.

The core mechanism of action highlights the targeted disruption of BBIP1, leading to the elucidation of its role in cellular homeostasis and protein synthesis. By silencing the BBIP1 gene, these cell lines allow researchers to assess changes in gene expression profiles, biochemical pathways, and the overall phenotype of the cells, which is crucial for detailed biological analysis. Given that BBIP1 is implicated in multiple disease states, particularly in oncology, these knockout cell lines offer significant insights that can be translated into clinical research settings.

In comparison to existing alternatives, BBIP1 Gene Knockout Cell Lines provide unrivaled specificity and reproducibility. Traditional methods for gene knockdown, such as RNA interference, may yield off-target effects or incomplete knockdowns, whereas the CRISPR-Cas9 approach ensures complete gene disruption, thereby enhancing the reliability of experimental outcomes. Furthermore, these cell lines are readily available and can be adapted for high-throughput screening, allowing researchers to efficiently assess the effects of pharmacological compounds targeting BBIP1.

The high level of precision and the depth of information obtainable from these knockout cell lines make them an invaluable asset for any laboratory focused on genetic studies, drug development, or deeper mechanistic understanding of cellular functions. By utilizing BBIP1 Gene Knockout Cell Lines, researchers can accelerate their discovery processes and contribute significantly to advancements in personalized medicine.

Our company is committed to providing cutting-edge biological tools like the BBIP1 Gene Knockout Cell Lines, driven by our expertise in gene editing technologies and our mission to support innovative research across various fields of biology and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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