Gene: BAZ2B
Official Full Name: bromodomain adjacent to zinc finger domain 2Bprovided by HGNC
Gene Summary: This gene belongs to the bromodomain gene family. Members of this gene family encode proteins that are integral components of chromatin remodeling complexes. The encoded protein showed strong preference for the activating H3K14Ac mark in a histone peptide screen, suggesting a potential role in transcriptional activation. This gene may be associated with susceptibility to sudden cardiac death (SCD). [provided by RefSeq, Aug 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26848 | BAZ2B Knockout cell line (HeLa) | Human | BAZ2B | 1:3~1:6 | Negative | Online Inquiry |
KO26849 | BAZ2B Knockout cell line (HCT 116) | Human | BAZ2B | 1:2~1:4 | Negative | Online Inquiry |
KO26850 | BAZ2B Knockout cell line (HEK293) | Human | BAZ2B | 1:3~1:6 | Negative | Online Inquiry |
KO26851 | BAZ2B Knockout cell line (A549) | Human | BAZ2B | 1:3~1:4 | Negative | Online Inquiry |
BAZ2B Gene Knockout Cell Lines are a revolutionary advancement in genetic research, providing researchers with a powerful tool to study the functions of the BAZ2B gene in various biological processes. By utilizing CRISPR/Cas9 technology, these cell lines have been meticulously engineered to exhibit complete knockout of the BAZ2B gene, enabling scientists to investigate its role in cellular functions, signaling pathways, and disease mechanisms with unprecedented accuracy.
The key mechanism behind these knockout cell lines involves the targeted cleavage of the DNA sequence that encodes BAZ2B, followed by the cellular repair processes that result in a disruption of the gene. This precise disruption allows researchers to analyze phenotypic changes and cellular responses, thereby offering insights into the gene's contribution to processes such as transcription regulation and chromatin remodeling, all of which are critical in development and cancer research.
The scientific importance of BAZ2B Gene Knockout Cell Lines lies in their broad applicability in both basic and applied research. They can be instrumental in elucidating the gene's involvement in specific diseases, providing a cellular model to test therapeutic interventions, and facilitating drug discovery efforts focused on modulating gene activity. These cell lines serve as invaluable resources for academic, pharmaceutical, and biotechnology sectors aiming to advance our understanding of gene function and potential disease targets.
Compared to alternative methods for genetic manipulation, such as siRNA or conventional knockout strategies, BAZ2B Gene Knockout Cell Lines offer several unique advantages. They provide permanent gene disruption, allowing for long-term studies and repeated experimental evaluations without the variability introduced by transient transfection methods. Additionally, the CRISPR/Cas9 approach ensures high specificity and efficiency, minimizing off-target effects and enhancing experimental reliability.
For researchers and clinicians, incorporating BAZ2B Gene Knockout Cell Lines into their studies can significantly accelerate the pace of discovery, making them an essential addition to any laboratory focused on genetics, molecular biology, or therapeutic development. Our company prides itself on delivering high-quality genetic tools that empower scientists. With our expertise in the field of genetic research and a commitment to excellence, we are your trusted partner in advancing scientific knowledge through innovative biological solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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