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ATXN1L Knockout Cell Lines

Gene: ATXN1L

Official Full Name: ataxin 1 likeprovided by HGNC

Gene Summary: Predicted to enable RNA binding activity and chromatin binding activity. Predicted to be involved in several processes, including learning or memory; negative regulation of transcription by RNA polymerase II; and social behavior. Predicted to act upstream of or within extracellular matrix organization; lung alveolus development; and positive regulation of hematopoietic stem cell proliferation. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19545 ATXN1L Knockout cell line (HeLa) Human ATXN1L 1:3~1:6 Negative Online Inquiry
KO19546 ATXN1L Knockout cell line (HCT 116) Human ATXN1L 1:2~1:4 Negative Online Inquiry
KO19547 ATXN1L Knockout cell line (HEK293) Human ATXN1L 1:3~1:6 Negative Online Inquiry
KO19548 ATXN1L Knockout cell line (A549) Human ATXN1L 1:3~1:4 Negative Online Inquiry

Background

ATXN1L Gene Knockout Cell Lines are advanced biological research tools specifically engineered to elucidate the role of the ataxin-1-like (ATXN1L) gene in cellular functions. Through the targeted disruption of this gene using CRISPR-Cas9 technology, these cell lines allow for the precise investigation of ATXN1L’s involvement in various biological pathways, particularly related to neuronal health and disease mechanisms.

The primary function of these knockout cell lines is to provide a controlled environment for researchers to study the physiological effects of ATXN1L gene deletion, which is instrumental in exploring neurodegenerative diseases, including spinocerebellar ataxia. By observing the resultant phenotypic changes at the cellular and molecular levels, scientists can gain insights into the pathology associated with this gene’s dysfunction.

The scientific importance of ATXN1L Gene Knockout Cell Lines extends to both fundamental research and applied clinical settings, enabling investigations into gene function and drug screening. Their application could lead to novel therapeutics aimed at conditions linked with ATXN1L dysregulation, thus serving a vital role in translational research.

What sets these cell lines apart from traditional models is their high specificity and reproducibility, ensuring reliable data that underpins the development of effective treatment strategies. Moreover, the flexibility of these cell lines allows for easy integration into various experimental paradigms, making them a versatile choice for laboratories.

For researchers and clinicians alike, the ATXN1L Gene Knockout Cell Lines offer substantial value through their contribution to understanding critical pathways in cell biology and disease. By using these cutting-edge tools, users can accelerate their findings and effectively translate their research into impactful solutions.

Our company prides itself on delivering high-quality, innovative genetic tools that meet the evolving needs of the scientific community, and the ATXN1L Gene Knockout Cell Lines stand as a testament to our commitment to excellence in biological research products.

Please note that all services are for research use only. Not intended for any clinical use.

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