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ATP9A Knockout Cell Lines

Gene: ATP9A

Official Full Name: ATPase phospholipid transporting 9A (putative)provided by HGNC

Gene Summary: Enables protease binding activity. Involved in negative regulation of exosomal secretion; regulation of endocytic recycling; and regulation of retrograde transport, endosome to Golgi. Located in several cellular components, including endosome; perinuclear region of cytoplasm; and trans-Golgi network membrane. Implicated in neurodevelopmental disorder with poor growth and behavioral abnormalities. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32313 ATP9A Knockout cell line (HeLa) Human ATP9A 1:3~1:6 Negative Online Inquiry
KO32314 ATP9A Knockout cell line (HCT 116) Human ATP9A 1:2~1:4 Negative Online Inquiry
KO32315 ATP9A Knockout cell line (HEK293) Human ATP9A 1:3~1:6 Negative Online Inquiry
KO32316 ATP9A Knockout cell line (A549) Human ATP9A 1:3~1:4 Negative Online Inquiry

Background

ATP9A Gene Knockout Cell Lines are specially engineered cell lines in which the ATP9A gene has been inactivated or "knocked out." ATP9A encodes a member of the P-type ATPase family, which is involved in lipid transport and cellular ion homeostasis. The knockout of this gene presents a powerful tool for researchers investigating the physiological and pathological roles of ATP9A in various biological processes, including cellular metabolism, endosomal function, and its potential links to diseases such as cancer and neurodegeneration.

The mechanism of action underlying these knockout cell lines allows for the examination of the effects of ATP9A absence on cellular behavior. Researchers can utilize these cell lines to dissect the pathways regulated by ATP9A and assess changes in cellular morphology, proliferation, and response to stimuli. This makes ATP9A Gene Knockout Cell Lines invaluable for translational studies, where understanding the molecular basis of disease can lead to identifying new therapeutic targets and strategies.

In comparison to other gene manipulation methods, such as CRISPR or traditional gene editing techniques, our ATP9A Gene Knockout Cell Lines offer a ready-to-use model that greatly accelerates research timelines. They provide consistent, reproducible results without the need for extensive prior optimization, ensuring high-quality data generation. Furthermore, these cell lines have undergone rigorous validation and characterization, establishing their integrity and reliability in research settings.

For researchers and clinicians, the ability to study ATP9A gene function in a controlled environment enables insights that can drive innovation in therapeutic development and biomarker evaluation. Our commitment to producing high-quality biological products is backed by years of expertise in genetic engineering and cell line development, ensuring that we provide solutions that meet the evolving needs of the scientific community. By choosing ATP9A Gene Knockout Cell Lines, you invest in a resource that enhances your research and contributes to advancing our understanding of complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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