Gene: ATP5IF1
Official Full Name: ATP synthase inhibitory factor subunit 1provided by HGNC
Gene Summary: Enables several functions, including ATPase binding activity; angiostatin binding activity; and mitochondrial proton-transporting ATP synthase complex binding activity. Involved in several processes, including mitochondrial depolarization; negative regulation of endothelial cell proliferation; and positive regulation of metabolic process. Located in cell surface and mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01793 | ATP5IF1 Knockout cell line (HeLa) | Human | ATP5IF1 | 1:3~1:6 | Negative | Online Inquiry |
KO01794 | ATP5IF1 Knockout cell line (HCT 116) | Human | ATP5IF1 | 1:2~1:4 | Negative | Online Inquiry |
KO01795 | ATP5IF1 Knockout cell line (HEK293) | Human | ATP5IF1 | 1:3~1:6 | Negative | Online Inquiry |
KO01796 | ATP5IF1 Knockout cell line (A549) | Human | ATP5IF1 | 1:3~1:4 | Negative | Online Inquiry |
ATP5IF1 Gene Knockout Cell Lines are genetically engineered cellular models designed to study the functional implications of ATP5IF1 gene disruption. This gene encodes a subunit of ATP synthase, a pivotal enzyme in ATP production, which plays a crucial role in cellular energy homeostasis. By creating knockout versions of this gene, researchers can investigate the downstream effects on mitochondrial function, energy metabolism, and associated cellular processes.
The primary mechanism of action involves the deletion or disruption of the ATP5IF1 gene, resulting in impaired ATP synthesis and aberrant regulation of oxidative phosphorylation pathways. These knockout cell lines can be utilized to explore various biochemical and physiological changes that occur due to energy deprivation or altered metabolic states, providing insights into disease models such as cancer, neurodegeneration, and metabolic disorders.
The scientific importance of ATP5IF1 Gene Knockout Cell Lines extends to their applications in both basic research and clinical investigations. They serve as valuable tools in drug discovery, allowing for the identification of compounds that may restore normal cellular function or target specific pathways altered in disease states. Furthermore, these cell models can aid in elucidating the role of mitochondrial dysfunction in various pathologies, enhancing our understanding of diseases linked to energy metabolism.
What sets our ATP5IF1 Gene Knockout Cell Lines apart from conventional cell models is their specificity, reliability, and robust characterization. These knockout lines are meticulously validated, ensuring consistent performance across experiments, making them indispensable for researchers seeking to develop targeted therapeutics or investigate specific biochemical pathways.
For researchers, clinicians, and biopharma developers, our ATP5IF1 Gene Knockout Cell Lines present an unparalleled resource to advance their investigations. By leveraging these precise models, users can generate reproducible results that contribute to a greater understanding of mitochondrial biology and therapeutic intervention strategies. Our company possesses extensive expertise in developing high-quality biological products, ensuring that our offerings empower the research community and facilitate groundbreaking discoveries in the field of cellular metabolism and beyond.
Please note that all services are for research use only. Not intended for any clinical use.
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