Gene: ASB13
Official Full Name: ankyrin repeat and SOCS box containing 13provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants, both protein-coding and not protein-coding, have been described for this gene. [provided by RefSeq, Nov 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19635 | ASB13 Knockout cell line (HeLa) | Human | ASB13 | 1:3~1:6 | Negative | Online Inquiry |
KO19636 | ASB13 Knockout cell line (HCT 116) | Human | ASB13 | 1:2~1:4 | Negative | Online Inquiry |
KO19637 | ASB13 Knockout cell line (HEK293) | Human | ASB13 | 1:3~1:6 | Negative | Online Inquiry |
KO19638 | ASB13 Knockout cell line (A549) | Human | ASB13 | 1:3~1:4 | Negative | Online Inquiry |
ASB13 Gene Knockout Cell Lines represent a groundbreaking tool in cellular and molecular biology, designed specifically for the study of the ASB13 gene’s functions and its implications in various biological processes. These cell lines are engineered using sophisticated genome editing techniques such as CRISPR/Cas9, allowing for precise and reliable disruption of the ASB13 gene. By knocking out this gene, researchers can analyze downstream effects on cellular pathways, gene expression, and phenotypic changes, providing invaluable insights into the gene's role in health and disease.
The primary function of the ASB13 Gene Knockout Cell Lines lies in their ability to serve as model systems for studying the involvement of the ASB13 gene in cellular processes like differentiation, proliferation, and apoptosis. Notably, ASB13 has been implicated in pathological conditions such as cancer, metabolic disorders, and neurodegenerative diseases. The knockout cells enable researchers to delineate the pathways affected by ASB13 and potentially identify novel therapeutic targets.
Scientifically, these cell lines hold immense value in both research and clinical settings, as they are essential for validating hypotheses regarding gene function and interaction in drug discovery, toxicity testing, and biomarker identification. The use of ASB13 knockout lines can accelerate the pace of research by providing clear models in which gene function is dissected without the interference of the normal allelic variants.
Compared to alternative gene knockout approaches, ASB13 Gene Knockout Cell Lines offer several advantages, including higher specificity, reproducibility, and the ability to perform high-throughput screening. Their versatile application across different cell types and experimental setups makes them a preferred choice for researchers focused on gene function and regulatory mechanisms.
In summary, ASB13 Gene Knockout Cell Lines are a powerful asset for any researcher or clinician looking to deepen their understanding of genomic influences on disease and develop targeted therapies. With our company’s commitment to innovation and quality in biological products, we equip scientists with the tools necessary to drive their research forward and unlock the mysteries of the ASB13 gene for therapeutic advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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