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ASAP3 Knockout Cell Lines

Gene: ASAP3

Official Full Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 3provided by HGNC

Gene Summary: This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19639 ASAP3 Knockout cell line (HeLa) Human ASAP3 1:3~1:6 Negative Online Inquiry
KO19640 ASAP3 Knockout cell line (HCT 116) Human ASAP3 1:2~1:4 Negative Online Inquiry
KO19641 ASAP3 Knockout cell line (HEK293) Human ASAP3 1:3~1:6 Negative Online Inquiry
KO19642 ASAP3 Knockout cell line (A549) Human ASAP3 1:3~1:4 Negative Online Inquiry

Background

ASAP3 Gene Knockout Cell Lines are specifically engineered cell lines that have undergone targeted gene disruption of the ASAP3 gene, a critical component involved in various cellular processes including migration, proliferation, and signaling pathways. Utilizing advanced CRISPR-Cas9 technology, these cell lines enable researchers to investigate the functional roles of ASAP3 in cellular dynamics and its implications in diseases such as cancer, neurodegeneration, and inflammatory disorders.

The primary mechanism of the ASAP3 knockout involves the precise editing of the gene sequence, resulting in a loss of function. By observing the phenotypic and molecular alterations following the gene disruption, scientists can explore how ASAP3 contributes to cell behavior and how its dysregulation can lead to pathology. This allows for a deeper understanding of its biological pathways, and potential therapeutic targets, enhancing the translational capacity of research findings into clinical applications.

The scientific importance of ASAP3 Gene Knockout Cell Lines is underscored by their versatility in various research settings, particularly in the fields of cancer biology and drug discovery. Researchers can utilize these models to elucidate the mechanisms of metastasis, validate drug targets, and screen for pharmacological agents. This comprehensive functionality positions these cell lines as an essential tool in preclinical studies.

What differentiates ASAP3 Gene Knockout Cell Lines from other genetic models is their high efficiency in gene editing and the robustness of their physiological relevance. Unlike general knockout approaches, these specific lines offer a simplified and more reliable platform for targeting the ASAP3 gene, resulting in reproducible data and expedited research timelines.

For researchers and clinicians, the value of ASAP3 Gene Knockout Cell Lines lies in their ability to facilitate impactful discoveries and potentially therapeutic innovations. By providing a quick and reliable means to investigate gene function, these cell lines enhance the understanding of fundamental biological processes while paving the way for future translational research.

As a leader in genetic engineering solutions, our company is dedicated to delivering cutting-edge products like the ASAP3 Gene Knockout Cell Lines, empowering scientists to make groundbreaking advancements in biological and medical research. With our extensive expertise and commitment to quality, we continue to support the scientific community by providing tools that drive discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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