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ARRDC1 Knockout Cell Lines

Gene: ARRDC1

Official Full Name: arrestin domain containing 1provided by HGNC

Gene Summary: Enables several functions, including arrestin family protein binding activity; ubiquitin protein ligase binding activity; and ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including extracellular vesicle biogenesis; negative regulation of Notch signaling pathway; and ubiquitin-dependent protein catabolic process. Located in cytoplasmic vesicle; extracellular vesicle; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22649 ARRDC1 Knockout cell line (HeLa) Human ARRDC1 1:3~1:6 Negative Online Inquiry
KO22650 ARRDC1 Knockout cell line (HCT 116) Human ARRDC1 1:2~1:4 Negative Online Inquiry
KO22651 ARRDC1 Knockout cell line (HEK293) Human ARRDC1 1:3~1:6 Negative Online Inquiry
KO22652 ARRDC1 Knockout cell line (A549) Human ARRDC1 1:3~1:4 Negative Online Inquiry

Background

ARRDC1 Gene Knockout Cell Lines are specifically engineered cellular models in which the ARRDC1 gene has been knocked out using advanced CRISPR-Cas9 technology. This gene plays a critical role in cellular processes, including endocytosis and membrane trafficking, influencing various signaling pathways integral to cellular homeostasis. By utilizing these knockout cell lines, researchers can effectively dissect the role of ARRDC1 in physiological and pathological contexts, including cancer and metabolic disorders.

The key mechanism of these cell lines involves the disruption of the ARRDC1 gene, leading to a loss of function that allows scientists to explore the downstream effects of its absence. This is particularly important for investigations into diseases where ARRDC1 activity is implicated, as well as for studies focused on cellular stress responses and receptor signal modulation. With these models, researchers can assess phenotypic changes, evaluate potential compensatory mechanisms, and identify novel therapeutic targets.

The scientific importance of ARRDC1 Gene Knockout Cell Lines extends to areas such as drug development, where understanding the influence of specific genes on treatment responses can facilitate personalized medicine approaches. Moreover, in-depth studies on ARRDC1 can yield insights into various cellular dysregulations and disease mechanisms, furthering our understanding of complex biological systems.

One of the key advantages of our ARRDC1 Gene Knockout Cell Lines is their reliability and reproducibility in experimental setups. Compared to other gene editing methods that may result in off-target effects, our CRISPR-Cas9 approach ensures precise gene disruption, offering greater confidence in experimental outcomes. Furthermore, these cell lines come with comprehensive characterization data, affording researchers ease of use and saving time on preliminary validation.

By incorporating ARRDC1 Gene Knockout Cell Lines into their research or clinical workflows, scientists and clinicians can accelerate discovery and enhance the accuracy of their studies. These cell lines are invaluable for probing gene functions and for applications involving cellular response assessments under varying conditions.

Our company prides itself on its commitment to advancing research through cutting-edge biological products. With a robust pipeline of expertly developed cell lines and a wealth of experience in the field, we are dedicated to supporting scientists in their quest for knowledge and innovation in biotechnology and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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