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ARPC5L Knockout Cell Lines

Gene: ARPC5L

Official Full Name: actin related protein 2/3 complex subunit 5 likeprovided by HGNC

Gene Summary: Predicted to enable actin filament binding activity. Predicted to be involved in Arp2/3 complex-mediated actin nucleation and cell migration. Located in extracellular exosome and focal adhesion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02075 ARPC5L Knockout cell line (HeLa) Human ARPC5L 1:3~1:6 Negative Online Inquiry
KO02076 ARPC5L Knockout cell line (HCT 116) Human ARPC5L 1:2~1:4 Negative Online Inquiry
KO02077 ARPC5L Knockout cell line (HEK293) Human ARPC5L 1:3~1:6 Negative Online Inquiry
KO02078 ARPC5L Knockout cell line (A549) Human ARPC5L 1:3~1:4 Negative Online Inquiry

Background

ARPC5L Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the ARPC5L gene, which encodes a vital component of the actin-regulating complexes involved in cytoskeletal dynamics. These cell lines are created through cutting-edge CRISPR-Cas9 technology, resulting in stable knockout configurations that allow researchers to investigate the role of ARPC5L in various biological processes, such as cell migration, adhesion, and proliferation, by alleviating the function of this gene.

The key mechanism of these knockout cell lines lies in the specific and precise disruption of the ARPC5L gene, which effectively negates its protein expression. By doing so, researchers can observe the phenotypic and behavioral changes that occur in cellular activity, providing insights into the gene's function in normal physiological conditions and disease states, such as cancer or developmental disorders. This model is particularly useful in elucidating molecular pathways associated with actin polymerization and its impact on cellular integrity and function.

The scientific importance of ARPC5L Gene Knockout Cell Lines is underscored by their wide applicability in both basic and applied research. In clinical settings, these cell lines can aid in drug discovery and therapeutics targeting cytoskeletal components and their associated pathways, potentially leading to innovative treatments for diseases characterized by cytoskeletal dysfunction.

What sets our ARPC5L Gene Knockout Cell Lines apart from other knockout models is their superior stability and reproducibility, ensuring consistent results across experiments. Furthermore, they come with comprehensive documentation and targeted technical support that enhances ease of use. Researchers and clinicians will find our product indispensable for advanced studies into the implications of ARPC5L in health and disease.

As a leader in genetic engineering solutions, our company is dedicated to developing high-quality biological products tailored to meet the rigorous demands of modern research and clinical applications, ensuring that scientists have the tools they need to drive innovation and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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